Literature DB >> 10712894

How cholesterol modulates the signal.

P W Ingham1.   

Abstract

By coupling to cholesterol, Hedgehog can be anchored to the cells where it is made, yet to act as a morphogen, it must be able to move away from its source. Novel genes have now been identified that control the release and dispersal of Hedgehog, shedding new light on the part played by cholesterol in these processes.

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Year:  2000        PMID: 10712894     DOI: 10.1016/s0960-9822(00)00346-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  8 in total

Review 1.  Developmental roles of heparan sulfate proteoglycans in Drosophila.

Authors:  Xinhua Lin; Norbert Perrimon
Journal:  Glycoconj J       Date:  2002 May-Jun       Impact factor: 2.916

Review 2.  The role of the Hedgehog signaling pathway in cancer: A comprehensive review.

Authors:  Ana Marija Skoda; Dora Simovic; Valentina Karin; Vedran Kardum; Semir Vranic; Ljiljana Serman
Journal:  Bosn J Basic Med Sci       Date:  2018-02-20       Impact factor: 3.363

Review 3.  Exploring Sonic Hedgehog Cell Signaling in Neurogenesis: Its Potential Role in Depressive Behavior.

Authors:  Tarapati Rana; Tapan Behl; Aayush Sehgal; Monika Sachdeva; Vineet Mehta; Neelam Sharma; Sukhbir Singh; Simona Bungau
Journal:  Neurochem Res       Date:  2021-03-30       Impact factor: 3.996

4.  Sonic hedgehog restricts adhesion and migration of neural crest cells independently of the Patched- Smoothened-Gli signaling pathway.

Authors:  S Testaz; A Jarov; K P Williams; L E Ling; V E Koteliansky; C Fournier-Thibault; J L Duband
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-09       Impact factor: 11.205

5.  A Functional and Putative Physiological Role of Calcitriol in Patched1/Smoothened Interaction.

Authors:  Benedikt Linder; Susanne Weber; Kai Dittmann; Jerzy Adamski; Heidi Hahn; Anja Uhmann
Journal:  J Biol Chem       Date:  2015-06-30       Impact factor: 5.157

Review 6.  Hedgehog signaling and its molecular perspective with cholesterol: a comprehensive review.

Authors:  Jyoti B Kaushal; Surinder K Batra; Satyanarayana Rachagani
Journal:  Cell Mol Life Sci       Date:  2022-04-29       Impact factor: 9.261

7.  The influenza virus ion channel and maturation cofactor M2 is a cholesterol-binding protein.

Authors:  Cornelia Schroeder; Harald Heider; Elisabeth Möncke-Buchner; Tse-I Lin
Journal:  Eur Biophys J       Date:  2004-06-25       Impact factor: 1.733

Review 8.  Hedgehog Signaling in Cancer: A Prospective Therapeutic Target for Eradicating Cancer Stem Cells.

Authors:  Ita Novita Sari; Lan Thi Hanh Phi; Nayoung Jun; Yoseph Toni Wijaya; Sanghyun Lee; Hyog Young Kwon
Journal:  Cells       Date:  2018-11-10       Impact factor: 6.600

  8 in total

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