Literature DB >> 10711240

Selective oestrogen receptor modulation: molecular pharmacology for the millennium.

A S Levenson1, V C Jordan.   

Abstract

Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors.

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Year:  1999        PMID： 10711240     DOI： 10.1016/s0959-8049(99)00297-x

Source DB:  PubMed          Journal:  Eur J Cancer        ISSN： 0959-8049            Impact factor:   9.162


  5 in total

1.  Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver.

Authors:  Rance Nault; Agnes L Forgacs; Edward Dere; Timothy R Zacharewski
Journal:  Toxicol Lett       Date:  2013-08-29       Impact factor: 4.372

2.  Benign endometrial adenofibroma and polyp in patients receiving tamoxifen: findings on transvaginal ultrasonography and magnetic resonance imaging.

Authors:  Akiko Ikuta; Yoshiaki Tanaka; Tomomi Mizokami; Akihiro Tsutsumi; Masahiro Sato; Maki Tanaka; Hideharu Kanzaki
Journal:  J Med Ultrason (2001)       Date:  2005-06       Impact factor: 1.314

3.  Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides.

Authors:  Chao Li; Yi-Xuan Cao; Ruo-Xing Jin; Kang-Jie Bian; Zi-Yang Qin; Quan Lan; Xi-Sheng Wang
Journal:  Chem Sci       Date:  2019-08-20       Impact factor: 9.825

4.  Molecular classification of selective oestrogen receptor modulators on the basis of gene expression profiles of breast cancer cells expressing oestrogen receptor alpha.

Authors:  A S Levenson; I L Kliakhandler; K M Svoboda; K M Pease; S A Kaiser; J E Ward; V C Jordan
Journal:  Br J Cancer       Date:  2002-08-12       Impact factor: 7.640

5.  The Effect of Selective Estrogen Receptor Modulators (SERMs) on the Tamoxifen Resistant Breast Cancer Cells.

Authors:  Bo Yoon Chang; Sae Am Kim; Bindu Malla; Sung Yeon Kim
Journal:  Toxicol Res       Date:  2011-06
  5 in total

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