| Literature DB >> 10709859 |
J Li1, T R Billiar.
Abstract
Nitric oxide (NO) has been shown to play important roles in modulating cell viability. Both proapoptotic and antiapoptotic functions of NO have been reported. This article discusses our current understanding on the mechanisms responsible for the dual actions of NO in regulating apoptosis and propose that one common mechanism for NO-mediated inhibition of apoptosis is the inhibition of caspases via nitrosylation.Entities:
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Year: 2000 PMID： 10709859 DOI： 10.1016/s0146-0005(00)80055-5
Source DB: PubMed Journal: Semin Perinatol ISSN： 0146-0005 Impact factor: 3.300