Literature DB >> 10708775

Computational model of the fluid dynamics in systemic-to-pulmonary shunts.

F Migliavacca1, G Dubini, G Pennati, R Pietrabissa, R Fumero, T Y Hsia, M R de Leval.   

Abstract

A systemic-to-pulmonary shunt is a connection created between the systemic and pulmonary arterial circulations in order to improve pulmonary perfusion in children with congenital heart diseases. Knowledge of the relationship between pressure and flow in this new, surgically created, cardiovascular district may be helpful in the clinical management of these patients, whose survival is critically dependent on the blood flow distribution between the pulmonary and systemic circulations. In this study a group of three-dimensional computational models of the shunt have been investigated under steady-state and pulsatile conditions by means of a finite element analysis. The model is used to quantify the effects of shunt diameter (D), curvature, angle, and pulsatility on the pressure-flow (DeltaP-Q) relationship of the shunt. Size of the shunt is the main regulator of pressure-flow relationship. Innominate arterial diameter and angles of insertion have less influence. Curvature of the shunt results in lower pressure drops. Inertial effects can be neglected. The following simplified formulae are derived: DeltaP=(0. 097Q+0.521Q(2))/D(4) and DeltaP=(0.096Q+0.393Q(2))/D(4) for the different shunt geometries investigated (straight and curved shunts, respectively).

Entities:  

Mesh:

Year:  2000        PMID: 10708775     DOI: 10.1016/s0021-9290(99)00219-5

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  7 in total

1.  Norwood procedure with non-valved right ventricle to pulmonary artery shunt improves ventricular energetics despite the presence of diastolic regurgitation: a theoretical analysis.

Authors:  Shuji Shimizu; Dai Une; Toshiaki Shishido; Atsunori Kamiya; Toru Kawada; Shunji Sano; Masaru Sugimachi
Journal:  J Physiol Sci       Date:  2011-08-10       Impact factor: 2.781

2.  Computational fluid dynamics characterization of blood flow in central aorta to pulmonary artery connections: importance of shunt angulation as a determinant of shear stress-induced thrombosis.

Authors:  Carey Celestin; Martin Guillot; Nancy Ross-Ascuitto; Robert Ascuitto
Journal:  Pediatr Cardiol       Date:  2014-11-18       Impact factor: 1.655

3.  Computational fluid dynamics in paediatric cardiac surgery.

Authors:  F Migliavacca; G Dubini; M de Leval
Journal:  Images Paediatr Cardiol       Date:  2000-01

4.  Tetralogy of Fallot Surgical Repair: Shunt Configurations, Ductus Arteriosus and the Circle of Willis.

Authors:  Senol Piskin; Gozde Unal; Ahmet Arnaz; Tayyar Sarioglu; Kerem Pekkan
Journal:  Cardiovasc Eng Technol       Date:  2017-04-05       Impact factor: 2.495

5.  Computational Fluid Dynamics Characterization of Two Patient-Specific Systemic-to-Pulmonary Shunts before and after Operation.

Authors:  Neichuan Zhang; Haiyun Yuan; Xiangyu Chen; Jiawei Liu; Qifei Jian; Meiping Huang; Kai Zhang
Journal:  Comput Math Methods Med       Date:  2019-02-03       Impact factor: 2.238

6.  Multiscale modelling of Potts shunt as a potential palliative treatment for suprasystemic idiopathic pulmonary artery hypertension: a paediatric case study.

Authors:  Sanjay Pant; Aleksander Sizarov; Angela Knepper; Gaëtan Gossard; Alberto Noferi; Younes Boudjemline; Irene Vignon-Clementel
Journal:  Biomech Model Mechanobiol       Date:  2022-01-09

Review 7.  Computational fluid dynamics models and congenital heart diseases.

Authors:  Giancarlo Pennati; Chiara Corsini; Tain-Yen Hsia; Francesco Migliavacca
Journal:  Front Pediatr       Date:  2013-02-26       Impact factor: 3.418

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.