| Literature DB >> 10708573 |
K Sasahara1, T Yamaoka, M Moritani, M Tanaka, H Iwahana, K Yoshimoto, J Miyagawa, Y Kuroda, M Itakura.
Abstract
We cloned a full-length mouse cDNA and its human homologue encoding a novel protein designated as "SR-25." In Northern blot analysis, SR-25 mRNA was expressed in all organs tested, and relatively abundant in testis and thymus. Deduced amino acid sequences of mouse SR-25 and human SR-25 showed 77.7% identity. SR-25 has a serine-arginine repeat (SR repeat) and two types of amino acid clusters: a serine cluster and a highly basic cluster. Based on the presence of many nuclear localizing signals and a similarity to RNA splicing proteins, SR-25 is strongly suggested to be a nuclear protein and may contribute to RNA splicing. Copyright 2000 Academic Press.Entities:
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Year: 2000 PMID： 10708573 DOI： 10.1006/bbrc.2000.2301
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575