Literature DB >> 10706469

Metastatic extramedullary plasmacytoma of the lung.

J Wang1, H S Pandha, J Treleaven, R Powles.   

Abstract

Extramedullary plasmacytomas (EMP) comprise 4% of all plasma cell neoplasms and commonly in the upper airway or digestive tract but rarely develop in the lungs. We present a case of primary pulmonary plasmacytoma in an 89 year old man, presented as a hilar mass with associated intrathoracic and extrathoracic lymph node metastases, but without evidence of myeloma. Treatment options for EMP include surgery, surgery and radiotherapy, surgery and chemotherapy or chemotherapy alone. Local recurrence rate is reported as 10-30%, with 17-48% progressing to multiple myeloma and median survival being 63-101 months. In view of the advanced age of this patient, who was initially treated unsuccessfully with intravenous cyclophosphamide and subsequently with two cycles of VAMP chemotherapy with good resolution of his disease, he is undergoing regular follow-up only.

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Mesh:

Year:  1999        PMID: 10706469     DOI: 10.3109/10428199909145749

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN: 1026-8022


  3 in total

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Authors:  Lauren Adelman; Victoria Larson; Thomas Sissener; Tim Spotswood
Journal:  Can Vet J       Date:  2014-01       Impact factor: 1.008

2.  Oral lesions and lymphoproliferative disorders.

Authors:  P Castellarin; G Pozzato; G Tirelli; R Di Lenarda; M Biasotto
Journal:  J Oncol       Date:  2010-09-01       Impact factor: 4.375

3.  Extramedullary plasmacytoma (EMP): Report of a case manifested as a mediastinal mass and multiple pulmonary nodules and review of literature.

Authors:  Shi-Ping Luh; Yih-Shyong Lai; Chung-Hong Tsai; Thomas Chang-Yao Tsao
Journal:  World J Surg Oncol       Date:  2007-10-27       Impact factor: 2.754

  3 in total

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