| Literature DB >> 10705747 |
I Razmilic, G Schmeda-Hirschmann.
Abstract
The labdane diterpene solidagenone and four semisynthetic derivatives were assessed for effects on the glucocorticoid-mediated signal transduction. Solidagenone and the derivatives proved to be active with IC50 values between 1 and 25 micrograms/mL. All compounds were cytotoxic towards L 1210, BHK and COS 7 cells with IC50 from 10-100 micrograms/mL.Entities:
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Year: 2000 PMID： 10705747 DOI： 10.1055/s-0029-1243119
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352