OBJECTIVE: To define the level of nitric oxide (NO) in the spermatic vein of patients with varicocele and its relation with male infertility. MATERIALS AND METHODS: Following physical and color Doppler ultrasonographic examination, whole blood samples were drawn from a peripheral vein and a dilated varicocele vein from fourteen patients with clinically palpable varicocele (G2-3) before ligation. NO levels in the serum were determined as total nitrite by Greiss reaction and results were compared with Mann-Whitney U test. RESULTS: NO levels in the internal spermatic vein were 36.05 +/- 8. 92 micromol/l, compared to 19.41 +/- 4.12 micromol/l in the peripheral vein and the difference was statistically significant (p < 0.01). CONCLUSION: In view of our results, increased NO levels in the dilated varicocele vein might be responsible for spermatozoa dysfunction.
OBJECTIVE: To define the level of nitric oxide (NO) in the spermatic vein of patients with varicocele and its relation with male infertility. MATERIALS AND METHODS: Following physical and color Doppler ultrasonographic examination, whole blood samples were drawn from a peripheral vein and a dilated varicocele vein from fourteen patients with clinically palpable varicocele (G2-3) before ligation. NO levels in the serum were determined as total nitrite by Greiss reaction and results were compared with Mann-Whitney U test. RESULTS: NO levels in the internal spermatic vein were 36.05 +/- 8. 92 micromol/l, compared to 19.41 +/- 4.12 micromol/l in the peripheral vein and the difference was statistically significant (p < 0.01). CONCLUSION: In view of our results, increased NO levels in the dilated varicocele vein might be responsible for spermatozoa dysfunction.
Authors: M Zavattaro; C Ceruti; G Motta; S Allasia; L Marinelli; C Di Bisceglie; M P Tagliabue; M Sibona; L Rolle; F Lanfranco Journal: J Endocrinol Invest Date: 2018-10-03 Impact factor: 4.256
Authors: Ismail Türker Köksal; Tibet Erdoğru; Hakan Gülkesen; Cem Sezer; Mustafa Usta; Akif Ciftçioğlu; Mehmet Baykara Journal: Int Urol Nephrol Date: 2004 Impact factor: 2.370
Authors: Oguzhan Yildiz; Husamettin Gul; Yaşar Ozgok; Onder Onguru; Mete Kilciler; Ahmet Aydin; Askin Isimer; A Cetin Harmankaya Journal: Urol Res Date: 2003-07-11