| Literature DB >> 10704801 |
M Korhonen1, H Niskanen, J Kiesvaara, J Yliruusi.
Abstract
The effect of surfactant on the rheological properties of some cream formulations was studied. Two surfactants from two different series were combined to determine the combination which yielded the most viscoelastic structure for creams. The surfactants were the soybean derivatives soya sterol, polyethylene glycol 10 soya sterol and polyethylene glycol 25 soya sterol and the sorbitol derivatives sorbitan monooleate and sorbitan trioleate. The rheological properties of the creams were studied using oscillation stress sweep, oscillation frequency sweep and viscosity tests. Droplet size distribution and conductivity of the creams were also determined. The combination polyethylene glycol 10 soya sterol and sorbitan trioleate yielded the most viscoelastic structure with linearly viscoelastic behaviour.Entities:
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Year: 2000 PMID： 10704801 DOI： 10.1016/s0378-5173(99)00464-0
Source DB: PubMed Journal: Int J Pharm ISSN： 0378-5173 Impact factor: 5.875