Literature DB >> 10704407

Gene silencing: shrinking the black box of RNAi.

C P Hunter1.   

Abstract

The mysterious mechanism whereby the mere presence of double-stranded RNA can inactivate specific genes is yielding its secrets. Recent results identifying cellular components required for RNAi in Caenorhabditis elegans indicate that the mechanism is conserved, ancient and may provide a defense against selfish DNA.

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Year:  2000        PMID: 10704407     DOI: 10.1016/s0960-9822(00)00325-0

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  5 in total

1.  Eph receptor tyrosine kinase-mediated formation of a topographic map in the Drosophila visual system.

Authors:  Richard Dearborn; Qi He; Sam Kunes; Yong Dai
Journal:  J Neurosci       Date:  2002-02-15       Impact factor: 6.167

2.  RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase.

Authors:  Henrik Martens; Jindrich Novotny; Jürgen Oberstrass; Theodore L Steck; Pamela Postlethwait; Wolfgang Nellen
Journal:  Mol Biol Cell       Date:  2002-02       Impact factor: 4.138

3.  Caenorhabditis elegans VEM-1, a novel membrane protein, regulates the guidance of ventral nerve cord-associated axons.

Authors:  Erik Runko; Zaven Kaprielian
Journal:  J Neurosci       Date:  2004-10-13       Impact factor: 6.167

4.  Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis.

Authors:  R Giet; D M Glover
Journal:  J Cell Biol       Date:  2001-02-19       Impact factor: 10.539

5.  Co-expression of Piwil2/Piwil4 in nucleus indicates poor prognosis of hepatocellular carcinoma.

Authors:  Guangping Zeng; Deying Zhang; Xing Liu; Qing Kang; Yiyao Fu; Bo Tang; Wenhao Guo; Yuanyuan Zhang; Guanghui Wei; Dawei He
Journal:  Oncotarget       Date:  2017-01-17
  5 in total

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