| Literature DB >> 10703608 |
M M Collins1, T Tang, R Slack, D Sintasath, R J Hartzman, J Ng, C K Hurley, J Ng, C K Hurley.
Abstract
The frequencies of alleles in the HLA-DRB1*01 family were determined in each of five US populations from a database of 82,979 individuals. Individuals typed as DR1 (or DRB1*01) comprised between 7.6%-21.3% of the individuals in each population group. Fifty-nine DR1 individuals were randomly selected from each group and subjected to high-resolution DNA typing by polymerase chain reaction using sequence-specific oligonucleotide probes. DRB1*0101 was the most common allele in the Caucasian, Asian/Pacific Islander, and Native American groups while the DRB1*0102 allele was found in the majority of African Americans and Hispanics. DRB1*0103 was present at a similar frequency in all populations. DRB1*0104, DRB1*0105, and DRB1*0106 alleles were not observed.Entities:
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Year: 2000 PMID： 10703608 DOI： 10.1034/j.1399-0039.2000.550108.x
Source DB: PubMed Journal: Tissue Antigens ISSN： 0001-2815