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Literature DB >> 10701703

The effects of mechanical forces on lung functions.

Abstract

The lung is a dynamic organ that is subjected to mechanical forces throughout development and adult life. This review article addresses the types of mechanical forces in the lung and their effects on development and normal lung functions. The effects of mechanical forces on the various different cell types of the lung are discussed, as are the mechanisms underlying mechanotransduction.

Mesh：

Year: 2000 PMID： 10701703 DOI： 10.1016/s0034-5687(99)00092-4

Source DB: PubMed Journal: Respir Physiol ISSN： 0034-5687

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Cited

62 in total

1. A concentration-dependent mechanism by which serum albumin inactivates replacement lung surfactants.

Authors: H E Warriner; J Ding; A J Waring; J A Zasadzinski
Journal: Biophys J Date: 2002-02 Impact factor: 4.033

2. Microrheology of human lung epithelial cells measured by atomic force microscopy.

Authors: Jordi Alcaraz; Lara Buscemi; Mireia Grabulosa; Xavier Trepat; Ben Fabry; Ramon Farré; Daniel Navajas
Journal: Biophys J Date: 2003-03 Impact factor: 4.033

3. Determination of alveolar epithelial cell phenotypes in fetal sheep: evidence for the involvement of basal lung expansion.

Authors: Sharon J Flecknoe; Megan J Wallace; Richard Harding; Stuart B Hooper
Journal: J Physiol Date: 2002-07-01 Impact factor: 5.182

The effects of mechanical forces on lung functions.

1. A concentration-dependent mechanism by which serum albumin inactivates replacement lung surfactants.

2. Microrheology of human lung epithelial cells measured by atomic force microscopy.

3. Determination of alveolar epithelial cell phenotypes in fetal sheep: evidence for the involvement of basal lung expansion.

4. Cytokines, neurokines or both? Mixed mechanisms of mechanical lung injury.

5. Genetic variation of SCNN1A influences lung diffusing capacity in cystic fibrosis.

Review 6. Review of cellular mechanotransduction on micropost substrates.

Review 7. Comparative analysis of the mechanical signals in lung development and compensatory growth.

8. Stretch increases alveolar epithelial permeability to uncharged micromolecules.

Review 9. Cellular stress failure in ventilator-injured lungs.

10. Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha.