Literature DB >> 10699230

Analysis of catechol-O-methyltransferase and 5-hydroxytryptamine transporter polymorphisms in patients at risk for suicide.

M J Russ1, H M Lachman, T Kashdan, T Saito, S Bajmakovic-Kacila.   

Abstract

Genotype frequencies of functional polymorphisms in the genes encoding the serotonin transporter (5-HTT) and the enzyme catechol-O-methyltransferase (COMT) were not different in 51 suicidal inpatients compared to 51 control subjects. Within the patient group, increased hopelessness and suicide ideation were associated with homozygosity of the 5-HTT high promotor activity allele.

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Year:  2000        PMID： 10699230     DOI： 10.1016/s0165-1781(00)00128-1

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  10 in total

1.  Neurobiology of suicidal behavior. An integration of biological and clinical findings.

Authors:  Juan J Carballo; Chibuikem P Akamnonu; Maria A Oquendo
Journal:  Arch Suicide Res       Date:  2008

Review 2.  Stress, genes and the biology of suicidal behavior.

Authors:  Dianne Currier; J John Mann
Journal:  Psychiatr Clin North Am       Date:  2008-06

3.  The COMT Met158 allele and violence in schizophrenia: a meta-analysis.

Authors:  Savita G Bhakta; Jian-Ping Zhang; Anil K Malhotra
Journal:  Schizophr Res       Date:  2012-07-10       Impact factor: 4.939

4.  Association study of a novel functional polymorphism of the serotonin transporter gene in bipolar disorder and suicidal behaviour.

Authors:  Vincenzo De Luca; Subi Tharmalingam; Nicole King; John Strauss; Natalie Bulgin; James L Kennedy
Journal:  Psychopharmacology (Berl)       Date:  2005-09-29       Impact factor: 4.530

5.  The COMT Val158Met polymorphism and cognition in depressed and nondepressed older adults.

Authors:  G G Potter; W D Taylor; D R McQuoid; D C Steffens; K A Welsh-Bohmer; K R R Krishnan
Journal:  Int J Geriatr Psychiatry       Date:  2009-10       Impact factor: 3.485

6.  No association of COMT Val158Met polymorphism with suicidal behavior or CSF monoamine metabolites in mood disorders.

Authors:  Gil Zalsman; Yung-yu Huang; Maria A Oquendo; David A Brent; Lucas Giner; Fatemeh Haghighi; Ainsley K Burke; Steven P Ellis; Dianne Currier; J John Mann
Journal:  Arch Suicide Res       Date:  2008

7.  No association between COMT val158met polymorphism and suicidal behavior: meta-analysis and new data.

Authors:  Carlos Tovilla-Zárate; Isela Juárez-Rojop; Teresa Ramón-Frias; Mario Villar-Soto; Sherezada Pool-García; Beatriz Camarena Medellín; Alma D Genis Mendoza; Lilia López Narvaez; Nicolini Humberto
Journal:  BMC Psychiatry       Date:  2011-09-21       Impact factor: 3.630

8.  Serotonin transporter gene polymorphism and psychiatric disorders: is there a link?

Authors:  Mushtaq A Margoob; Dhuha Mushtaq
Journal:  Indian J Psychiatry       Date:  2011-10       Impact factor: 1.759

9.  The role of COMT gene Val108/158Met polymorphism in suicidal behavior: systematic review and updated meta-analysis.

Authors:  Thelma Beatriz González-Castro; Yazmín Hernández-Díaz; Isela Esther Juárez-Rojop; María Lilia López-Narváez; Carlos Alfonso Tovilla-Zárate; Julian Ramírez-Bello; Nonanzit Pérez-Hernández; Alma Delia Genis-Mendoza; Ana Fresan; Crystell Guadalupe Guzmán-Priego
Journal:  Neuropsychiatr Dis Treat       Date:  2018-09-28       Impact factor: 2.570

10.  Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy.

Authors:  George A Kenna; Nick Roder-Hanna; Lorenzo Leggio; William H Zywiak; James Clifford; Steven Edwards; John A Kenna; Jessica Shoaff; Robert M Swift
Journal:  Pharmgenomics Pers Med       Date:  2012-01-13
  10 in total

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