| Literature DB >> 10698339 |
N K Wong1, M Kojima, J Dobó, G Ambrus, R B Sim.
Abstract
There has been rapid progress in determining the mechanism by which complement is activated by the complex formed between Mannose-Binding Lectin and its associated proteases (MASPs). MBL and the MASPs are of low abundance, but are similar to the more abundant C1q-C1r2s2 complex (C1), which has been extensively investigated. In this review we summarise recent findings on MBL-MASPs' structure. enzymic activity and regulation, and compare MBL-MASPs with C1.Entities:
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Year: 1999 PMID: 10698339 DOI: 10.1016/s0161-5890(99)00106-6
Source DB: PubMed Journal: Mol Immunol ISSN: 0161-5890 Impact factor: 4.407