PURPOSE: To describe the clinical picture and electrophysiological findings in acquired unilateral nyctalopia. METHODS: A patient who had acquired unilateral visual loss with normal fundus was followed for a period of 2.5 years with basic ophthalmological examinations including standard electroretinogram and photopic on and off responses. RESULTS: A 46-year-old woman suffered from acquired unilateral nyctalopia. She complained of photopsia and blurred vision in her left eye. The initial examination of the left eye showed 1+ cells in the anterior chamber and a granular appearance in the fovea. After 1 month of treatment she still complained of photopsia in her left eye. Ophthalmoscopy and fluorescein angiography revealed no abnormality in either eye. A bright flash electroretinogram (ERG) in the left eye was a negative shape. Photopic ERG elicited by a 150 ms stimulus showed a depressed b-wave and enhanced a- and d-waves in the left eye. CONCLUSIONS: This ERG waveform suggested that the transmission between photoreceptor and on-bipolar cell might be affected by idiopathic retinal disease.
PURPOSE: To describe the clinical picture and electrophysiological findings in acquired unilateral nyctalopia. METHODS: A patient who had acquired unilateral visual loss with normal fundus was followed for a period of 2.5 years with basic ophthalmological examinations including standard electroretinogram and photopic on and off responses. RESULTS: A 46-year-old woman suffered from acquired unilateral nyctalopia. She complained of photopsia and blurred vision in her left eye. The initial examination of the left eye showed 1+ cells in the anterior chamber and a granular appearance in the fovea. After 1 month of treatment she still complained of photopsia in her left eye. Ophthalmoscopy and fluorescein angiography revealed no abnormality in either eye. A bright flash electroretinogram (ERG) in the left eye was a negative shape. Photopic ERG elicited by a 150 ms stimulus showed a depressed b-wave and enhanced a- and d-waves in the left eye. CONCLUSIONS: This ERG waveform suggested that the transmission between photoreceptor and on-bipolar cell might be affected by idiopathic retinal disease.
Authors: A G Robson; E C Richardson; A H C Koh; C E Pavesio; P G Hykin; A Calcagni; E M Graham; G E Holder Journal: Br J Ophthalmol Date: 2005-12 Impact factor: 4.638