Literature DB >> 10695672

Funalenone, a novel collagenase inhibitor produced by Aspergillus niger.

J Inokoshi1, K Shiomi, R Masuma, H Tanaka, H Yamada, S Omura.   

Abstract

Funalenone, a phenalene compound that inhibits type I collagenase (MMP-1), was isolated from mycelium of Aspergillus niger FO-5904 by solvent extaction, ODS column chromatography, Sephadex LH-20 column chromatography and reversed phase HPLC. Funalenone inhibited 50% of type I collagenase activity at a concentration of 170 microM, but inhibited 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 microM.

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Year:  1999        PMID： 10695672     DOI： 10.7164/antibiotics.52.1095

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  10 in total

1.  Does the chemistry of fungal pigments demand the existence of photoactivated defense strategies in basidiomycetes?

Authors:  Bianka Siewert
Journal:  Photochem Photobiol Sci       Date:  2021-03-18       Impact factor: 3.982

2.  Preparation of phenalenes and hydronaphthacenes through tandem alkyne Fischer-carbene complex coupling and inter- or intramolecular Diels-Alder reactions.

Authors:  Rajesh Kumar Patti; Shaofeng Duan; Zhipeng Wang; James W Herndon
Journal:  Tetrahedron Lett       Date:  2011-08-10       Impact factor: 2.415

3.  Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88.

Authors:  Mikael R Andersen; Margarita P Salazar; Peter J Schaap; Peter J I van de Vondervoort; David Culley; Jette Thykaer; Jens C Frisvad; Kristian F Nielsen; Richard Albang; Kaj Albermann; Randy M Berka; Gerhard H Braus; Susanna A Braus-Stromeyer; Luis M Corrochano; Ziyu Dai; Piet W M van Dijck; Gerald Hofmann; Linda L Lasure; Jon K Magnuson; Hildegard Menke; Martin Meijer; Susan L Meijer; Jakob B Nielsen; Michael L Nielsen; Albert J J van Ooyen; Herman J Pel; Lars Poulsen; Rob A Samson; Hein Stam; Adrian Tsang; Johannes M van den Brink; Alex Atkins; Andrea Aerts; Harris Shapiro; Jasmyn Pangilinan; Asaf Salamov; Yigong Lou; Erika Lindquist; Susan Lucas; Jane Grimwood; Igor V Grigoriev; Christian P Kubicek; Diego Martinez; Noël N M E van Peij; Johannes A Roubos; Jens Nielsen; Scott E Baker
Journal:  Genome Res       Date:  2011-05-04       Impact factor: 9.043

4.  Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis.

Authors:  Jixun Zhan; G M Kamal B Gunaherath; E M Kithsiri Wijeratne; A A Leslie Gunatilaka
Journal:  Phytochemistry       Date:  2006-12-05       Impact factor: 4.072

5.  Inhibitory effect of Aspergillus fumigatus extract on matrix metalloproteinases expression.

Authors:  Farshid Saadat; Kamiar Zomorodian; Mohammad Pezeshki; Sassan Rezaie; Mohammad Reza Khorramizadeh
Journal:  Mycopathologia       Date:  2004-07       Impact factor: 2.574

6.  Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase.

Authors:  Shu-Shan Gao; Abing Duan; Wei Xu; Peiyuan Yu; Leibniz Hang; K N Houk; Yi Tang
Journal:  J Am Chem Soc       Date:  2016-03-22       Impact factor: 15.419

7.  Rasamsonia, a new genus comprising thermotolerant and thermophilic Talaromyces and Geosmithia species.

Authors:  J Houbraken; H Spierenburg; J C Frisvad
Journal:  Antonie Van Leeuwenhoek       Date:  2011-10-02       Impact factor: 2.271

Review 8.  Potential of small-molecule fungal metabolites in antiviral chemotherapy.

Authors:  Biswajit G Roy
Journal:  Antivir Chem Chemother       Date:  2017-07-23

Review 9.  Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei.

Authors:  Jens C Frisvad; Lars L H Møller; Thomas O Larsen; Ravi Kumar; José Arnau
Journal:  Appl Microbiol Biotechnol       Date:  2018-10-06       Impact factor: 4.813

Review 10.  Cend1, a Story with Many Tales: From Regulation of Cell Cycle Progression/Exit of Neural Stem Cells to Brain Structure and Function.

Authors:  Maria Gaitanou; Katerina Segklia; Rebecca Matsas
Journal:  Stem Cells Int       Date:  2019-05-02       Impact factor: 5.443
  10 in total

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