J O Thomas1, B O Ogunsanwo, A O Ogunbiyi. 1. Department of Pathology, University College Hospital, Ibadan, Nigeria. dementia.uch@skannet.com.ng
Abstract
OBJECTIVE: To find out the pattern, trend and site distribution of extranodal lymphomas in Ibadan. DESIGN: Case series. SETTING: Department of Pathology, University College Hospital. SUBJECTS: All cases of malignant lymphomas with extranodal manifestations between 1981 and 1998. MAIN OUTCOME MEASURES: Frequency and distribution of primary extranodal lymphomas. RESULTS: Extranodal lymphomas constituted 9.8% of non-Hodgkin's lymphomas(NHLs) during the period, increasing from 8.5% of NHLs from 1980 to 1990 to 12.4% from 1991 to 1998. During the entire 18 year period the nasal/nasopharynx, gastro-intestinal tract (GIT), tonsils and skin were the most commonly affected sites constituting 20.2%, 19.3%, 14.3% and 13.4%, respectively of all extranodal lymphomas. However, between 1980 and 1991 the GIT was the most commonly affected site (26.1%) followed by the nasal/nasopharyngeal region (11.6%). The involvement of the nasopharyngeal area during the second period of the study accounted for 32.0%. CONCLUSION: The reasons for this changing trend are unknown and the significance of HIV infection in this regard is uncertain.
OBJECTIVE: To find out the pattern, trend and site distribution of extranodal lymphomas in Ibadan. DESIGN: Case series. SETTING: Department of Pathology, University College Hospital. SUBJECTS: All cases of malignant lymphomas with extranodal manifestations between 1981 and 1998. MAIN OUTCOME MEASURES: Frequency and distribution of primary extranodal lymphomas. RESULTS:Extranodal lymphomas constituted 9.8% of non-Hodgkin's lymphomas(NHLs) during the period, increasing from 8.5% of NHLs from 1980 to 1990 to 12.4% from 1991 to 1998. During the entire 18 year period the nasal/nasopharynx, gastro-intestinal tract (GIT), tonsils and skin were the most commonly affected sites constituting 20.2%, 19.3%, 14.3% and 13.4%, respectively of all extranodal lymphomas. However, between 1980 and 1991 the GIT was the most commonly affected site (26.1%) followed by the nasal/nasopharyngeal region (11.6%). The involvement of the nasopharyngeal area during the second period of the study accounted for 32.0%. CONCLUSION: The reasons for this changing trend are unknown and the significance of HIV infection in this regard is uncertain.
Authors: A Olayiwola Oluwasola; John A Olaniyi; Jesse A Otegbayo; Gabriel O Ogun; Titi S Akingbola; Cornelius O Ukah; Effiong E U Akang; Yetunde A Aken'Ova Journal: J Health Popul Nutr Date: 2011-08 Impact factor: 2.000