| Literature DB >> 10694881 |
M A McNiven1, H Cao, K R Pitts, Y Yoon.
Abstract
The large GTPase dynamin is a mechanoenzyme that mediates the liberation of nascent clathrin-coated pits from the plasma membrane during endocytosis. Recently, this enzyme has been demonstrated to comprise an extensive family of related proteins that have been implicated in a large variety of vesicle trafficking events during endocytosis, secretion and even maintenance of mitochondrial form. The potential contributions by the dynamin family to these diverse but related functions are discussed.Mesh:
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Year: 2000 PMID: 10694881 DOI: 10.1016/s0968-0004(99)01538-8
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807