| Literature DB >> 1069452 |
Abstract
Twelve endometrial cancers have been observed before and during progestogen treatment. Eight were well-differentiated and displayed an objective response. It was essentially characterized by a volumetric reduction of the nucleus and the disappearance of tetraploid nuclei. The DNA content remained diploid or near-diploid. Reduction of nuclear non DNA proteins under hormonal treatment is suggested.Entities:
Keywords: Biology; Cancer; Clinical Research; Cytologic Effects; Diseases; Endocrine System; Endometrial Cancer; Genitalia; Genitalia, Female; Hormones; Neoplasms; Physiology; Progestational Hormones; Progesterone--side effects; Progesterone--therapeutic use; Research Methodology; Urogenital System; Uterus
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Year: 1976 PMID： 1069452
Source DB: PubMed Journal: Acta Cytol ISSN： 0001-5547 Impact factor: 2.319