Literature DB >> 10693825

Scrapie transmission in Britain: a recipe for a mathematical model.

A R Mclean1, A Hoek, L J Hoinville, M B Gravenor.   

Abstract

Responses to an anonymous postal survey concerning scrapie are analysed. Risk factors associated with farms that have had scrapie are identified as size, geographical region, lambing practices and holding of certain breeds. Further analysis of farms that have scrapie only in bought-in animals reveals that such farms tend to breed a smaller proportion of their replacement animals than farms without scrapie. Farms that have had scrapie in home-bred animals have attributes associated with breeding many animals: large numbers of rams bought, few ewes bought, and many animals that are home-bred. The demography of British sheep farms as described by size, breeds, purchasing behaviour, age structure and proportion of animals that are home-bred is summarized. British farms with scrapie reveal certain special features: they have more sheep that are found dead, more elderly ewes and more cases of scab.

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Year:  1999        PMID: 10693825      PMCID: PMC1690487          DOI: 10.1098/rspb.1999.0956

Source DB:  PubMed          Journal:  Proc Biol Sci        ISSN: 0962-8452            Impact factor:   5.349


  15 in total

1.  Scrapie occurrence in Great Britain.

Authors:  L Hoinville; A R McLean; A Hoek; M B Gravenor; J Wilesmith
Journal:  Vet Rec       Date:  1999-10-02       Impact factor: 2.695

2.  The epidemiology of BSE in cattle herds in Great Britain. II. Model construction and analysis of transmission dynamics.

Authors:  N M Ferguson; C A Donnelly; M E Woolhouse; R M Anderson
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-07-29       Impact factor: 6.237

3.  A questionnaire survey of the prevalence of scrapie in sheep in Britain.

Authors:  K L Morgan; K Nicholas; M J Glover; A P Hall
Journal:  Vet Rec       Date:  1990-10-13       Impact factor: 2.695

Review 4.  A review of the epidemiology of scrapie in sheep.

Authors:  L J Hoinville
Journal:  Rev Sci Tech       Date:  1996-09       Impact factor: 1.181

5.  Pre-clinical and clinical diagnosis of scrapie by detection of PrP protein in tissues of sheep.

Authors:  Y Ikegami; M Ito; H Isomura; E Momotani; K Sasaki; Y Muramatsu; N Ishiguro; M Shinagawa
Journal:  Vet Rec       Date:  1991-03-23       Impact factor: 2.695

6.  Prevalence and incidence of scrapie in The Netherlands: a questionnaire survey.

Authors:  B E Schreuder; M C de Jong; J J Pekelder; P Vellema; A J Bröker; H Betcke
Journal:  Vet Rec       Date:  1993-08-28       Impact factor: 2.695

7.  Scrapie associated fibrils in found dead sheep.

Authors:  A M Clark; M Dawson; A C Scott
Journal:  Vet Rec       Date:  1994-06-18       Impact factor: 2.695

8.  The estimation of age-related rates of infection from case notifications and serological data.

Authors:  B T Grenfell; R M Anderson
Journal:  J Hyg (Lond)       Date:  1985-10

9.  Spread of scrapie to sheep and goats by oral dosing with foetal membranes from scrapie-affected sheep.

Authors:  I H Pattison; M N Hoare; J N Jebbett; W A Watson
Journal:  Vet Rec       Date:  1972-04-22       Impact factor: 2.695

10.  Transmission dynamics and epidemiology of BSE in British cattle.

Authors:  R M Anderson; C A Donnelly; N M Ferguson; M E Woolhouse; C J Watt; H J Udy; S MaWhinney; S P Dunstan; T R Southwood; J W Wilesmith; J B Ryan; L J Hoinville; J E Hillerton; A R Austin; G A Wells
Journal:  Nature       Date:  1996-08-29       Impact factor: 49.962

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  14 in total

1.  The signature of scrapie: differences in the PrP genotype profile of scrapie-affected and scrapie-free UK sheep flocks.

Authors:  M Baylis; F Houston; W Goldmann; N Hunter; A R McLean
Journal:  Proc Biol Sci       Date:  2000-10-22       Impact factor: 5.349

2.  Epidemiological analysis of data for scrapie in Great Britain.

Authors:  T J Hagenaars; C A Donnelly; N M Ferguson
Journal:  Epidemiol Infect       Date:  2006-04       Impact factor: 2.451

3.  Prevalence of sheep infected with classical scrapie in Great Britain: integrating multiple sources of surveillance data for 2002.

Authors:  Simon Gubbins
Journal:  J R Soc Interface       Date:  2008-11-06       Impact factor: 4.118

Review 4.  The role of mathematical modelling in understanding the epidemiology and control of sheep transmissible spongiform encephalopathies: a review.

Authors:  Simon Gubbins; Suzanne Touzeau; Thomas J Hagenaars
Journal:  Vet Res       Date:  2010-02-23       Impact factor: 3.683

5.  Prevalence of scrapie infection in Great Britain: interpreting the results of the 1997-1998 abattoir survey.

Authors:  Simon Gubbins; Marion M Simmons; Kumar Sivam; Cerian R Webb; Linda J Hoinville
Journal:  Proc Biol Sci       Date:  2003-09-22       Impact factor: 5.349

6.  Quantifying the risk from ovine BSE and the impact of control strategies.

Authors:  Helen R Fryer; Matthew Baylis; Kumar Sivam; Angela R McLean
Journal:  Proc Biol Sci       Date:  2007-06-22       Impact factor: 5.349

7.  Use of a preclinical test in the control of classical scrapie.

Authors:  L A Boden; F Houston; H R Fryer; R R Kao
Journal:  J Gen Virol       Date:  2010-06-23       Impact factor: 3.891

8.  Spatial distribution of the active surveillance of sheep scrapie in Great Britain: an exploratory analysis.

Authors:  Colin P D Birch; Ambrose C Chikukwa; Kieran Hyder; Victor J Del Rio Vilas
Journal:  BMC Vet Res       Date:  2009-07-16       Impact factor: 2.741

9.  Demographic risk factors for classical and atypical scrapie in Great Britain.

Authors:  Darren M Green; Victor J Del Rio Vilas; Colin P D Birch; Jethro Johnson; Istvan Z Kiss; Noel D McCarthy; Rowland R Kao
Journal:  J Gen Virol       Date:  2007-12       Impact factor: 3.891

10.  On the question of proportionality of the count of observed scrapie cases and the size of holding.

Authors:  Dankmar Böhning; Victor J Del Rio Vilas
Journal:  BMC Vet Res       Date:  2009-05-06       Impact factor: 2.741

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