Literature DB >> 10693742

Characterization of Trypanozoon isolates using a repeated coding sequence and microsatellite markers.

N Biteau1, F Bringaud, W Gibson, P Truc, T Baltz.   

Abstract

Genetic variation of microsatellite loci is a widely used method for linkage analysis, individual identification or inter-population studies. Here we analyse a repeated DNA coding sequence and eleven new microsatellites identified within the Trypanosoma (Trypanozoon) brucei genome. Ninety-seven isolates belonging to the five species and subspecies Trypanosoma evansi, T. equiperdum, T. brucei brucei, T. b. rhodesiense and T. b. gambiense were compared regarding the genetic patterns of these markers. The results reveal a great heterogeneity of the genotypes related to the repeated coding sequence and five microsatellites, some of which show a high degree of polymorphism. This allows us to define group-specific genotypes or alleles; in particular, we show that one specific pattern clearly segregates the human pathogen T. b. gambiense group I.

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Year:  2000        PMID： 10693742

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  13 in total

1.  Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length.

Authors:  Sergio Callejas; Vanessa Leech; Christopher Reitter; Sara Melville
Journal:  Genome Res       Date:  2006-08-09       Impact factor: 9.043

Review 2.  The origins of the trypanosome genome strains Trypanosoma brucei brucei TREU 927, T. b. gambiense DAL 972, T. vivax Y486 and T. congolense IL3000.

Authors:  Wendy Gibson
Journal:  Parasit Vectors       Date:  2012-04-07       Impact factor: 3.876

3.  Molecular profiles of Trypanosoma brucei, T. evansi and T. equiperdum stocks revealed by the random amplified polymorphic DNA method.

Authors:  Zhao-Rong Lun; An-Xing Li; Xiao-Guang Chen; Li-Xin Lu; Xing-Quan Zhu
Journal:  Parasitol Res       Date:  2004-01-16       Impact factor: 2.289

4.  Genetic characterization and phylogenetic analysis of Trypanosoma evansi in Iranian dromedary camels.

Authors:  Mehrdad Pourjafar; Khalil Badiei; Hassan Sharifiyazdi; Aliasghar Chalmeh; Mojtaba Naghib; Marzieh Babazadeh; Amir Mootabi Alavi; Narges Hosseini Joshani-Zadeh
Journal:  Parasitol Res       Date:  2012-09-25       Impact factor: 2.289

5.  Population genetics of Trypanosoma brucei gambiense, the agent of sleeping sickness in Western Africa.

Authors:  Mathurin Koffi; Thierry De Meeûs; Bruno Bucheton; Philippe Solano; Mamadou Camara; Dramane Kaba; Gérard Cuny; Francisco J Ayala; Vincent Jamonneau
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-23       Impact factor: 11.205

6.  Population sub-structuring among Trypanosoma evansi stocks.

Authors:  Z K Njiru; C C Constantine
Journal:  Parasitol Res       Date:  2007-06-22       Impact factor: 2.289

7.  Identification of different trypanosome species in the mid-guts of tsetse flies of the Malanga (Kimpese) sleeping sickness focus of the Democratic Republic of Congo.

Authors:  Gustave Simo; Barberine Silatsa; Njiokou Flobert; Pascal Lutumba; Philemon Mansinsa; Joule Madinga; Emile Manzambi; Reginald De Deken; Tazoacha Asonganyi
Journal:  Parasit Vectors       Date:  2012-09-19       Impact factor: 3.876

8.  Population genetics of Trypanosoma evansi from camel in the Sudan.

Authors:  Bashir Salim; Thierry de Meeûs; Mohammed A Bakheit; Joseph Kamau; Ichiro Nakamura; Chihiro Sugimoto
Journal:  PLoS Negl Trop Dis       Date:  2011-06-07

9.  Species concepts for trypanosomes: from morphological to molecular definitions?

Authors:  Wendy Gibson
Journal:  Kinetoplastid Biol Dis       Date:  2003-10-28

10.  Population genetics of Trypanosoma brucei circulating in Glossina palpalis palpalis and domestic animals of the Fontem sleeping sickness focus of Cameroon.

Authors:  Gustave Simo; Guy Roger Njitchouang; Tresor Tito Tanekou Melachio; Flobert Njiokou; Gerard Cuny; Asonganyi Tazoacha
Journal:  Parasit Vectors       Date:  2014-04-01       Impact factor: 3.876
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