Literature DB >> 1069365

Motilin effects on gastrointestinal motility and lower esophageal sphincter (LES) pressure in dogs.

H M Jennewein, R Bauer, H Hummelt, G Lepsin, R Siewert, F Waldeck.   

Abstract

Natural porcine motilin induces phasic contractions of the lower esophageal sphincter in dogs. These contractions are related to gastric contractions, which have the characteristics of interdigestive-motility patterns. Duodenal alkalinization produces an insignificant LES pressure increase after 5 minutes. No effect of motilin was observed when using isolated canine muscle strips.

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Year:  1976        PMID： 1069365

Source DB:  PubMed          Journal:  Scand J Gastroenterol Suppl        ISSN： 0085-5928


  5 in total

1.  Changes in plasma motilin concentration and gastrointestinal contractile activity in conscious dogs.

Authors:  Z Itoh; S Takeuchi; I Aizawa; K Mori; T Taminato; Y Seino; H Imura; N Yanaihara
Journal:  Am J Dig Dis       Date:  1978-10

2.  The effect of motilin on the gastrointestinal propulsion in rats.

Authors:  S Nakazawa; K Segawa; H Hidano; Y Tsukamoto; M Aichi; T Ichikawa
Journal:  Gastroenterol Jpn       Date:  1978

3.  Control of lower-esophageal-sphincter contractile activity by motilin in conscious dogs.

Authors:  Z Itoh; I Aizawa; R Honda; K Hiwatashi; E F Couch
Journal:  Am J Dig Dis       Date:  1978-04

4.  Release of motilin by oral and intravenous nutrients in man.

Authors:  N D Christofides; S R Bloom; H S Besterman; T E Adrian; M A Ghatei
Journal:  Gut       Date:  1979-02       Impact factor: 23.059

Review 5.  Motilin Comparative Study: Structure, Distribution, Receptors, and Gastrointestinal Motility.

Authors:  Takio Kitazawa; Hiroyuki Kaiya
Journal:  Front Endocrinol (Lausanne)       Date:  2021-08-23       Impact factor: 5.555
  5 in total

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