Literature DB >> 10691722

A new bioactive triene aldehyde from the marine sponge Leucetta microraphis.

K Watanabe1, Y Tsuda, M Iwashima, K Iguchi.   

Abstract

A new triene aldehyde, (2E,6Z,9Z)-2-methyl-2,6,9-icosatrienal (1), was isolated from a MeOH extract of the Okinawan marine sponge Leucetta microraphis. The structure of 1 was determined by spectroscopic analysis. Three imidazole alkaloids, leucettamine B, preclathridine A, and (9E)-clathridine 9-N-(2-sulfoethyl)imine, were also obtained and identified. Compound 1 showed moderate growth-inhibitory activity toward HeLa S3 cells.

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Year:  2000        PMID: 10691722     DOI: 10.1021/np9903503

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

Review 1.  Recent progress in neuroactive marine natural products.

Authors:  Ryuichi Sakai; Geoffrey T Swanson
Journal:  Nat Prod Rep       Date:  2014-01-17       Impact factor: 13.423

2.  Two new imidazole alkaloids from Leucetta chagosensis sponge.

Authors:  Wafaa H B Hassan; Areej M Al-Taweel; Peter Proksch
Journal:  Saudi Pharm J       Date:  2009-11-10       Impact factor: 4.330

  2 in total

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