Literature DB >> 10691680

The PPARs: from orphan receptors to drug discovery.

T M Willson1, P J Brown, D D Sternbach, B R Henke.   

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Year:  2000        PMID: 10691680     DOI: 10.1021/jm990554g

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  361 in total

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3.  Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo.

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Review 6.  Diet, fatty acids, and regulation of genes important for heart disease.

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8.  Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models.

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Journal:  Br J Pharmacol       Date:  2003-09-01       Impact factor: 8.739

9.  Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.

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Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

10.  Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma.

Authors:  Andrew C Li; Christoph J Binder; Alejandra Gutierrez; Kathleen K Brown; Christine R Plotkin; Jennifer W Pattison; Annabel F Valledor; Roger A Davis; Timothy M Willson; Joseph L Witztum; Wulf Palinski; Christopher K Glass
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