Literature DB >> 10689347

Finding the genes that direct mammalian development : ENU mutagenesis in the mouse.

K V Anderson1.   

Abstract

The genetic control of mammalian embryogenesis is not well understood. N-ethyl-N-nitrosourea (ENU) mutagenesis screens in the mouse provide a route to identify more of the genes that are required for mammalian development. The characterization of ENU-induced mutations can build on the resources provided by the mouse and human genome projects to help define the tissue interactions and signaling pathways that direct early mammalian development.

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Year:  2000        PMID： 10689347     DOI： 10.1016/s0168-9525(99)01921-6

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  17 in total

1.  Embryo emergent: elucidating the cell biology of development. The Santa Cruz Conference on Developmental Biology 2000.

Authors:  M Halpern; G Seydoux
Journal:  EMBO Rep       Date:  2000-12       Impact factor: 8.807

2.  Whole-genome profiling of mutagenesis in Caenorhabditis elegans.

Authors:  Stephane Flibotte; Mark L Edgley; Iasha Chaudhry; Jon Taylor; Sarah E Neil; Aleksandra Rogula; Rick Zapf; Martin Hirst; Yaron Butterfield; Steven J Jones; Marco A Marra; Robert J Barstead; Donald G Moerman
Journal:  Genetics       Date:  2010-05-03       Impact factor: 4.562

3.  The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta.

Authors:  Loydie A Jerome-Majewska; Tala Achkar; Li Luo; Floria Lupu; Elizabeth Lacy
Journal:  Dev Biol       Date:  2010-02-21       Impact factor: 3.582

4.  High-throughput functional screen of mouse gastrula cDNA libraries reveals new components of endoderm and mesoderm specification.

Authors:  Eric Chiao; Jeff Leonard; Kari Dickinson; Julie C Baker
Journal:  Genome Res       Date:  2005-01       Impact factor: 9.043

Review 5.  N-ethyl-N-nitrosourea mutagenesis: boarding the mouse mutant express.

Authors:  Sabine P Cordes
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

6.  A versatile gene trap to visualize and interrogate the function of the vertebrate proteome.

Authors:  Le A Trinh; Tatiana Hochgreb; Matthew Graham; David Wu; Frederique Ruf-Zamojski; Chathurani S Jayasena; Ankur Saxena; Rasheeda Hawk; Aidyl Gonzalez-Serricchio; Alana Dixson; Elly Chow; Constanza Gonzales; Ho-Yin Leung; Ilana Solomon; Marianne Bronner-Fraser; Sean G Megason; Scott E Fraser
Journal:  Genes Dev       Date:  2011-11-01       Impact factor: 11.361

7.  TRIM28 is required by the mouse KRAB domain protein ZFP568 to control convergent extension and morphogenesis of extra-embryonic tissues.

Authors:  Maho Shibata; Kristin E Blauvelt; Karel F Liem; María J García-García
Journal:  Development       Date:  2011-12       Impact factor: 6.868

Review 8.  Zebrafish--an emerging genetic model for the study of cytokines and hematopoiesis in the era of functional genomics.

Authors:  G J Lieschke
Journal:  Int J Hematol       Date:  2001-01       Impact factor: 2.490

9.  The expanding role of mouse genetics for understanding human biology and disease.

Authors:  Duc Nguyen; Tian Xu
Journal:  Dis Model Mech       Date:  2008 Jul-Aug       Impact factor: 5.758

10.  A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

Authors:  Seungshin Ha; Rolf W Stottmann; Andrew J Furley; David R Beier
Journal:  Cereb Cortex       Date:  2013-08-22       Impact factor: 5.357
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