Literature DB >> 10689333

The prophylactic effects of artemether against Schistosoma japonicum infections.

S H Xiao1, M Booth, M Tanner.   

Abstract

The fight against schistosomiasis in China has been very effective in reducing the number of infections across the country. However, the drug of choice, praziquantel, has no prophylactic effect, which reduces its efficacy in high transmission areas. This situation has prompted efforts to find prophylactic compounds, the most promising of which is the drug artemether. In this article, Xiao Shuhua, Mark Booth and Marcel Tanner review the results of laboratory tests and field trials of artemether against schistosomiasis in China.

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Year:  2000        PMID: 10689333     DOI: 10.1016/s0169-4758(99)01601-4

Source DB:  PubMed          Journal:  Parasitol Today        ISSN: 0169-4758


  38 in total

Review 1.  Combination chemotherapy of schistosomiasis in laboratory studies and clinical trials.

Authors:  Jürg Utzinger; Jennifer Keiser; Xiao Shuhua; Marcel Tanner; Burton H Singer
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

2.  Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.

Authors:  Shu-hua Xiao; Jing-yan Mei; Pei-ying Jiao
Journal:  Parasitol Res       Date:  2010-10-05       Impact factor: 2.289

3.  Further observation on histopathological alterations of adult Schistosoma japonicum harbored in mice following treatment with mefloquine at a smaller single dose.

Authors:  Shu-Hua Xiao; Chao-Wei Zhang
Journal:  Parasitol Res       Date:  2010-06-08       Impact factor: 2.289

4.  Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice.

Authors:  Hong-jun Li; Wei Wang; Guo-li Qu; You-zi Li; Yong-hui Tao; Yun-tian Xing; Xiao-ting Wang; Yang Dai; Jian-ying Wei; Jian-rong Dai; Gerald C Coles; You-sheng Liang
Journal:  Parasitol Res       Date:  2011-10-18       Impact factor: 2.289

5.  Effectiveness of mefloquine against Clonorchis sinensis in rats and Paragonimus westermani in dogs.

Authors:  Shu-hua Xiao; Jian Xue; Xu Li-li; Yong-nian Zhang; Hui-qing Qiang
Journal:  Parasitol Res       Date:  2010-08-03       Impact factor: 2.289

6.  Confocal laser scanning microscopic observation on adult Schistosoma japonicum harbored in mice following treatment with single-dose mefloquine.

Authors:  Shu-Hua Xiao; Jun Sun; Jian Xue
Journal:  Parasitol Res       Date:  2011-12-27       Impact factor: 2.289

Review 7.  Schistosomiasis in the People's Republic of China: prospects and challenges for the 21st century.

Authors:  A G Ross; A C Sleigh; Y Li; G M Davis; G M Williams; Z Jiang; Z Feng; D P McManus
Journal:  Clin Microbiol Rev       Date:  2001-04       Impact factor: 26.132

8.  Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum.

Authors:  Wei Wang; Tian-Yu Li; Yuan Ji; Guo-Li Qu; Yi-Li Qian; Hong-Jun Li; Jian-Rong Dai; You-Sheng Liang
Journal:  Parasitol Res       Date:  2013-12-11       Impact factor: 2.289

9.  Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols.

Authors:  Juliana B R Corrêa Soares; Diego Menezes; Marcos A Vannier-Santos; Antonio Ferreira-Pereira; Giulliana T Almeida; Thiago M Venancio; Sergio Verjovski-Almeida; Vincent K Zishiri; David Kuter; Roger Hunter; Timothy J Egan; Marcus F Oliveira
Journal:  PLoS Negl Trop Dis       Date:  2009-07-14

10.  In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species.

Authors:  Shu-Hua Xiao; Jennifer Keiser; Jacques Chollet; Jürg Utzinger; Yuxiang Dong; Yvette Endriss; Jonathan L Vennerstrom; Marcel Tanner
Journal:  Antimicrob Agents Chemother       Date:  2007-02-05       Impact factor: 5.191

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