Literature DB >> 10689303

Tyrosine kinase SYK: essential functions for immunoreceptor signalling.

M Turner1, E Schweighoffer, F Colucci, J P Di Santo, V L Tybulewicz.   

Abstract

The tyrosine kinase SYK plays critical roles in signalling through immune receptors. Gene-targeting studies have identified the cell types that require SYK for development and function, and the receptors that use SYK as well as their downstream signalling effectors. There is also evidence of a role for SYK in non-immune cells and in the maintenance of vascular integrity.

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Year:  2000        PMID: 10689303     DOI: 10.1016/s0167-5699(99)01574-1

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  98 in total

1.  BLNK mediates Syk-dependent Btk activation.

Authors:  Y Baba; S Hashimoto; M Matsushita; D Watanabe; T Kishimoto; T Kurosaki; S Tsukada
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-13       Impact factor: 11.205

2.  Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement.

Authors:  R Paolini; R Molfetta; M Piccoli; L Frati; A Santoni
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-07       Impact factor: 11.205

Review 3.  Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia.

Authors:  Kumudha Balakrishnan; Varsha Gandhi
Journal:  Expert Opin Investig Drugs       Date:  2012-03-09       Impact factor: 6.206

4.  Coupling of Fcγ receptor I to Fcγ receptor IIb by SRC kinase mediates C-reactive protein impairment of endothelial function.

Authors:  Nathan C Sundgren; Weifei Zhu; Ivan S Yuhanna; Ken L Chambliss; Mohamed Ahmed; Keiji Tanigaki; Michihisa Umetani; Chieko Mineo; Philip W Shaul
Journal:  Circ Res       Date:  2011-09-22       Impact factor: 17.367

Review 5.  Pathways of oncogene-induced senescence in human melanocytic cells.

Authors:  Rajat Bansal; Mikhail A Nikiforov
Journal:  Cell Cycle       Date:  2010-07-03       Impact factor: 4.534

6.  Picornaviruses.

Authors:  Tobias J Tuthill; Elisabetta Groppelli; James M Hogle; David J Rowlands
Journal:  Curr Top Microbiol Immunol       Date:  2010       Impact factor: 4.291

7.  Discovery of Lanraplenib (GS-9876): A Once-Daily Spleen Tyrosine Kinase Inhibitor for Autoimmune Diseases.

Authors:  Peter Blomgren; Jayaraman Chandrasekhar; Julie A Di Paolo; Wanchi Fung; Guoju Geng; Carmen Ip; Randall Jones; Jeffrey E Kropf; Eric B Lansdon; Seung Lee; Jennifer R Lo; Scott A Mitchell; Bernard Murray; Chris Pohlmeyer; Aaron Schmitt; Kimberly Suekawa-Pirrone; Sarah Wise; Jin-Ming Xiong; Jianjun Xu; Helen Yu; Zhongdong Zhao; Kevin S Currie
Journal:  ACS Med Chem Lett       Date:  2020-02-12       Impact factor: 4.345

8.  Yeast glucan particles activate murine resident macrophages to secrete proinflammatory cytokines via MyD88- and Syk kinase-dependent pathways.

Authors:  Bing Li; Daniel Cramer; Stephanie Wagner; Richard Hansen; Chelsea King; Shelly Kakar; Chuanlin Ding; Jun Yan
Journal:  Clin Immunol       Date:  2007-06-14       Impact factor: 3.969

9.  Tyrosine residues direct the ubiquitination and degradation of the NY-1 hantavirus G1 cytoplasmic tail.

Authors:  Erika Geimonen; Imelyn Fernandez; Irina N Gavrilovskaya; Erich R Mackow
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

10.  Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.

Authors:  Olivier Bailet; Nina Fenouille; Patricia Abbe; Guillaume Robert; Stéphane Rocchi; Nadège Gonthier; Christophe Denoyelle; Michel Ticchioni; Jean-Paul Ortonne; Robert Ballotti; Marcel Deckert; Sophie Tartare-Deckert
Journal:  Cancer Res       Date:  2009-03-17       Impact factor: 12.701

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