| Literature DB >> 10687875 |
M E Garín-Aguilar1, J E Luna, M Soto-Hernández, G Valencia del Toro, M M Vázquez.
Abstract
Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested.Entities:
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Year: 2000 PMID: 10687875 DOI: 10.1016/s0378-8741(99)00121-x
Source DB: PubMed Journal: J Ethnopharmacol ISSN: 0378-8741 Impact factor: 4.360