| Literature DB >> 10685013 |
Abstract
Cyanide is a chemical widely used in industry, and is a major environmental pollutant. Its toxicity is caused by inhibition of cytochrome oxidase resulting in histotoxic hypoxia. The effect of sublethal doses of cyanide on memory and hippocampal neurotransmitters was studied in male Wistar strain albino rats. Cyanide reduced the memory along with reduction in the levels of dopamine and 5-hydroxytryptamine in the hippocampus. Pre-existing malnutrition in the animals exaggerated these effects.Entities:
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Year: 2000 PMID: 10685013 DOI: 10.1016/s0278-6915(99)00118-0
Source DB: PubMed Journal: Food Chem Toxicol ISSN: 0278-6915 Impact factor: 6.023