Literature DB >> 10684982

Structural conservation and variation among U5 small nuclear RNAs from trypanosomatid protozoa.

M N Schnare1, M W Gray.   

Abstract

U5 snRNAs in trypanosomatid protozoa do not contain the trimethylguanosine cap structures that are often targeted in snRNA isolation procedures. As a result, the trypanosomatids are not well represented in the database of available U5 snRNA sequences. We have isolated and determined the sequence of the U5 snRNA from Crithidia fasciculata. Comparison with previously published trypanosomatid U5 snRNA sequences allows us to deduce the pattern of structural conservation and variation among these very divergent snRNA molecules.

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Year:  2000        PMID： 10684982     DOI： 10.1016/s0167-4781(00)00009-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  3 in total

1.  The spliced leader-associated RNA is a trypanosome-specific sn(o) RNA that has the potential to guide pseudouridine formation on the SL RNA.

Authors:  Xue-Hai Liang; Yu-Xin Xu; Shulamit Michaeli
Journal:  RNA       Date:  2002-02       Impact factor: 4.942

Review 2.  Unconventional rules of small nuclear RNA transcription and cap modification in trypanosomatids.

Authors:  Christian Tschudi; Elisabetta Ullut
Journal:  Gene Expr       Date:  2002

3.  The 28S-18S rDNA intergenic spacer from Crithidia fasciculata: repeated sequences, length heterogeneity, putative processing sites and potential interactions between U3 small nucleolar RNA and the ribosomal RNA precursor.

Authors:  M N Schnare; J C Collings; D F Spencer; M W Gray
Journal:  Nucleic Acids Res       Date:  2000-09-15       Impact factor: 16.971
  3 in total

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