Literature DB >> 10679388

Extrinsic regulators of epithelial tumor progression: metalloproteinases.

G Bergers1, L M Coussens.   

Abstract

Extracellular metal-dependent proteinases regulate cell behavior by remodeling stromal and cell surface proteins, thereby influencing cell recruitment, cell shape, motility, proliferation, survival, genomic (in)stability, and differentiation. In recent years, the importance of proteinase-induced signaling has been underscored by evidence that altered regulation of cell-extracellular matrix and cell-cell interactions by proteinases can contribute, in a causal manner, to neoplastic progression.

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Year:  2000        PMID： 10679388     DOI： 10.1016/s0959-437x(99)00043-x

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  38 in total

Review 1.  Order and disorder: the role of extracellular matrix in epithelial cancer.

Authors:  Derek Radisky; John Muschler; Mina J Bissell
Journal:  Cancer Invest       Date:  2002       Impact factor: 2.176

2.  Analysis of the transcriptional program induced by Raf in epithelial cells.

Authors:  A Schulze; K Lehmann; H B Jefferies; M McMahon; J Downward
Journal:  Genes Dev       Date:  2001-04-15       Impact factor: 11.361

3.  Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis.

Authors:  Karim Si-Tayeb; Arnaud Monvoisin; Claire Mazzocco; Sébastien Lepreux; Marion Decossas; Gaëlle Cubel; Danièle Taras; Jean-Frédéric Blanc; Derrick R Robinson; Jean Rosenbaum
Journal:  Am J Pathol       Date:  2006-10       Impact factor: 4.307

4.  Hypertensive vascular remodeling was inhibited by Xuezhikang through the regulation of Fibulin-3 and MMPs in spontaneously hypertensive rats.

Authors:  Zhong-Wei Lin; Zhuo Wang; Gui-Ping Zhu; Bo-Wei Li; Wen-Lin Xie; Ding-Cheng Xiang
Journal:  Int J Clin Exp Med       Date:  2015-02-15

5.  beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter.

Authors:  S Hapke; M Gawaz; K Dehne; J Köhler; J F Marshall; H Graeff; M Schmitt; U Reuning; E Lengyel
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

6.  CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling.

Authors:  Wei-Hsuan Yu; J Frederick Woessner; John D McNeish; Ivan Stamenkovic
Journal:  Genes Dev       Date:  2002-02-01       Impact factor: 11.361

7.  GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2.

Authors:  Liquan Yang; Scott Friedland; Nancy Corson; Lei Xu
Journal:  Cancer Res       Date:  2013-12-19       Impact factor: 12.701

8.  Retention of proteins and metalloproteins in open tubular capillary electrochromatography with etched chemically modified columns.

Authors:  Joseph J Pesek; Maria T Matyska; Vasudha Salgotra
Journal:  Electrophoresis       Date:  2008-09       Impact factor: 3.535

Review 9.  Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development.

Authors:  Lidiya S Orlichenko; Derek C Radisky
Journal:  Clin Exp Metastasis       Date:  2008-02-20       Impact factor: 5.150

10.  Connective tissue growth factor regulates retinal neovascularization through p53 protein-dependent transactivation of the matrix metalloproteinase (MMP)-2 gene.

Authors:  Hembindu Chintala; Haibo Liu; Rahul Parmar; Monika Kamalska; Yoon Ji Kim; David Lovett; Maria B Grant; Brahim Chaqour
Journal:  J Biol Chem       Date:  2012-10-09       Impact factor: 5.157
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