Literature DB >> 10678691

Implicit and explicit memory: a functional dissociation in persons with Down syndrome.

S Vicari1, S Bellucci, G A Carlesimo.   

Abstract

This study aimed at investigating implicit and explicit long-term memory functioning in subjects with Down syndrome (DS) compared to Mental-Age (MA) matched normal children. For this purpose, tests of verbal and visuo-perceptual explicit memory, verbal and visual repetition priming and procedural learning tasks were administered to 14 DS and 20 MA subjects. Our results document comparable implicit memory abilities in the two groups. In contrast, regarding explicit memory, normal children performed better than DS individuals. These results reveal a functional dissociation between implicit and explicit memory in subjects with DS. Theoretical and rehabilitative implications are discussed.

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Year:  2000        PMID: 10678691     DOI: 10.1016/s0028-3932(99)00081-0

Source DB:  PubMed          Journal:  Neuropsychologia        ISSN: 0028-3932            Impact factor:   3.139


  26 in total

Review 1.  Down syndrome: the brain in trisomic mode.

Authors:  Mara Dierssen
Journal:  Nat Rev Neurosci       Date:  2012-12       Impact factor: 34.870

2.  Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.

Authors:  Alexander M Kleschevnikov; Jessica Yu; Jeesun Kim; Larisa V Lysenko; Zheng Zeng; Y Eugene Yu; William C Mobley
Journal:  Neurobiol Dis       Date:  2017-03-22       Impact factor: 5.996

3.  The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome.

Authors:  Jesse E Hanson; Martina Blank; Ricardo A Valenzuela; Craig C Garner; Daniel V Madison
Journal:  J Physiol       Date:  2006-12-07       Impact factor: 5.182

4.  DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1.

Authors:  Paul A Kelly; Zohra Rahmani
Journal:  Mol Biol Cell       Date:  2005-05-25       Impact factor: 4.138

5.  Episodic-like memory in Ts65Dn, a mouse model of Down syndrome.

Authors:  Fabian Fernandez; Craig C Garner
Journal:  Behav Brain Res       Date:  2007-09-19       Impact factor: 3.332

6.  Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4.

Authors:  Jan Hendrik Sitz; Marcel Tigges; Karsten Baumgärtel; Leonid G Khaspekov; Beat Lutz
Journal:  Mol Cell Biol       Date:  2004-07       Impact factor: 4.272

7.  Prefrontal-hippocampal functional connectivity encodes recognition memory and is impaired in intellectual disability.

Authors:  Maria Alemany-González; Thomas Gener; Pau Nebot; Marta Vilademunt; Mara Dierssen; M Victoria Puig
Journal:  Proc Natl Acad Sci U S A       Date:  2020-05-11       Impact factor: 11.205

8.  Everyday Memory in People with Down Syndrome.

Authors:  Yingying Yang; Zachary M Himmelberger; Trent Robinson; Megan Davis; Frances Conners; Edward Merrill
Journal:  Brain Sci       Date:  2021-04-27

9.  Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome.

Authors:  Fiorenza Stagni; Jacopo Magistretti; Sandra Guidi; Elisabetta Ciani; Chiara Mangano; Laura Calzà; Renata Bartesaghi
Journal:  PLoS One       Date:  2013-04-19       Impact factor: 3.240

10.  A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.

Authors:  Patricia Lopes Pereira; Laetitia Magnol; Ignasi Sahún; Véronique Brault; Arnaud Duchon; Paola Prandini; Agnès Gruart; Jean-Charles Bizot; Bernadette Chadefaux-Vekemans; Samuel Deutsch; Fabrice Trovero; José María Delgado-García; Stylianos E Antonarakis; Mara Dierssen; Yann Herault
Journal:  Hum Mol Genet       Date:  2009-09-26       Impact factor: 6.150

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