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Literature DB >> 10674986

Tubby-like protein 1 as an autoantigen in cancer-associated retinopathy.

T Kikuchi¹, J Arai, H Shibuki, H Kawashima, N Yoshimura.

Abstract

Cancer-associated retinopathy (CAR) is a rare paraneoplastic syndrome that is characterized by retinal degeneration. Two cDNA clones, recoverin and tubby-like protein 1 (TULP1), were isolated from a human retinal cDNA library by using serum from a CAR patient as the probe. Both recoverin and TULP1 are retina-specific protein, and TULP1 is a member of tubby gene family. A determination of the recognized amino acid sequence of TULP1 by the patient serum and immunohistochemical studies on the distribution of TULP1 in the retina were done in this study.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2000 PMID： 10674986 DOI： 10.1016/s0165-5728(99)00163-0

Source DB: PubMed Journal: J Neuroimmunol ISSN： 0165-5728 Impact factor: 3.478

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Cited

11 in total

Review 1. Retinopathies associated with antiretinal antibodies.

Authors: J J Hooks; M O Tso; B Detrick
Journal: Clin Diagn Lab Immunol Date: 2001-09

2. Autoantibodies to photoreceptor membrane proteins and outer plexiform layer in patients with cancer-associated retinopathy.

Authors: R Peek; B G Dijkstra; B Meek; R W A M Kuijpers
Journal: Clin Exp Immunol Date: 2002-06 Impact factor: 4.330

Review 3. The need for standardization of antiretinal antibody detection and measurement.

Authors: Farzin Forooghian; Ian M Macdonald; John R Heckenlively; Elise Héon; Lynn K Gordon; John J Hooks; Barbara Detrick; Robert B Nussenblatt
Journal: Am J Ophthalmol Date: 2008-07-30 Impact factor: 5.258

4. Update on paraneoplastic neurologic disorders.

Authors: Myrna R Rosenfeld; Josep Dalmau
Journal: Oncologist Date: 2010-05-17

5. The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses.

Authors: Silke Wahl; Venkat Giri Magupalli; Mayur Dembla; Rashmi Katiyar; Karin Schwarz; Louise Köblitz; Kannan Alpadi; Elmar Krause; Jens Rettig; Ching-Hwa Sung; Andrew F X Goldberg; Frank Schmitz
Journal: J Neurosci Date: 2016-02-24 Impact factor: 6.167

Tubby-like protein 1 as an autoantigen in cancer-associated retinopathy.

Review 1. Retinopathies associated with antiretinal antibodies.

2. Autoantibodies to photoreceptor membrane proteins and outer plexiform layer in patients with cancer-associated retinopathy.

Review 3. The need for standardization of antiretinal antibody detection and measurement.

4. Update on paraneoplastic neurologic disorders.

5. The Disease Protein Tulp1 Is Essential for Periactive Zone Endocytosis in Photoreceptor Ribbon Synapses.

Review 6. The enigma of autoimmune retinopathy.

7. Current Techniques to Accurately Measure Anti-retinal Autoantibodies.

8. Serum Autoantibody Profiling of Patients with Paraneoplastic and Non-Paraneoplastic Autoimmune Retinopathy.

9. Identification of α-fodrin as an autoantigen in experimental coronavirus retinopathy (ECOR).

Review 10. Are Anti-Retinal Autoantibodies a Cause or a Consequence of Retinal Degeneration in Autoimmune Retinopathies?