| Literature DB >> 10673049 |
T Naas1, L Poirel, P Nordmann.
Abstract
Polymerase chain reaction-amplification and subsequent sequencing of the variable region of a novel integron, In51, from Pseudomonas aeruginosa revealed the presence of a novel aminoglycoside adenylyltransferase gene, aadA6, together with an open reading frame of unknown function, orfD. AADA6 enzyme has only 75% amino acid identity with AADA1 and is able to confer high level resistance to streptomycin and spectinomycin in Escherichia coli.Entities:
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Year: 1999 PMID: 10673049 DOI: 10.1016/s0167-4781(99)00202-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002