Literature DB >> 10672278

Mechanisms of selective neuronal cell death due to thiamine deficiency.

K Todd1, R F Butterworth.   

Abstract

Multiple mechanisms contribute to the selective brain lesions observed in WKS and experimental thiamine deficiency. Recent evidence of early microglial activation and increased free radical production suggest that oxidative stress processes play an important early role in the brain damage associated with thiamine deficiency.

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Year:  1999        PMID： 10672278     DOI： 10.1111/j.1749-6632.1999.tb07866.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  27 in total

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7.  Differential effects of systemic and intraseptal administration of the acetylcholinesterase inhibitor tacrine on the recovery of spatial behavior in an animal model of diencephalic amnesia.

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10.  Selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia.

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