BACKGROUND: A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors > or =54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. METHODS: A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. RESULTS: Dual versus single transplants from donors > or =54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching. CONCLUSIONS: Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors > or =54 years of age.
BACKGROUND: A novel but controversial method to increase the utilization of aged donor kidneys is the transplantation of both kidneys as a dual transplant. Initial single-center reports demonstrated outcomes similar to single kidneys from younger donors. In this report, we compare outcome in recipients of kidneys from donors > or =54 years of age who received a single kidney transplant reported to the United Network for Organ Sharing Scientific Registry versus a dual kidney transplant reported to the Dual Kidney Registry. METHODS: A retrospective analysis was performed, comparing four donor and nine recipient and outcome variables between recipients of a single versus a dual transplant between March 1993 and March 1999. RESULTS: Dual versus single transplants from donors > or =54 years of age have a significantly decreased incidence of delayed graft function, and lower serum creatinines up to 2 years after transplant despite having kidneys from significantly older donors with poorer HLA matching. CONCLUSIONS: Dual kidney transplants improve graft performance and outcome in recipients of kidneys from donors > or =54 years of age.
Authors: Robert J Stratta; Michael S Rohr; Aimee K Sundberg; Greg Armstrong; Gloria Hairston; Erica Hartmann; Alan C Farney; Julie Roskopf; Samy S Iskandar; Patricia L Adams Journal: Ann Surg Date: 2004-05 Impact factor: 12.969
Authors: Ramesh Saxena; Xueqing Yu; Mauricio Giraldo; Juan Arenas; Miguel Vazquez; Christopher Y Lu; Nosratola D Vaziri; Fred G Silva; Xin J Zhou Journal: Int Urol Nephrol Date: 2008-11-07 Impact factor: 2.370
Authors: B Tanriover; S Mohan; D J Cohen; J Radhakrishnan; T L Nickolas; P W Stone; D S Tsapepas; R J Crew; G K Dube; P R Sandoval; B Samstein; E Dogan; R S Gaston; J N Tanriover; L E Ratner; M A Hardy Journal: Am J Transplant Date: 2014-02 Impact factor: 8.086