Literature DB >> 10669779

A polymorphism in the mouse crg-2/IP-10 gene complicates chemokine gene expression analysis using a commercial ribonuclease protection assay.

W Hallensleben1, L Biro, C Sauder, J Hausmann, V C Asensio, I L Campbell, P Staeheli.   

Abstract

The use of multiprobe RPAs is becoming an increasingly popular method for the detection and quantitation of RNA levels in cells and tissues. Here we report that due to a polymorphism in the 3'-noncoding region of the mouse Crg-2/IP-10 gene, the mCK-5 chemokine probe set available from Pharmingen can yield aberrant signal patterns with RNA samples from BALB/c, MRL and possibly other mouse strains that may lead to false conclusions regarding expression of the Crg-2/IP-10 and MCP-1 genes.

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Year:  2000        PMID： 10669779     DOI： 10.1016/s0022-1759(99)00197-0

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  8 in total

1.  Matrix metalloproteinase expression correlates with virulence following neurotropic mouse hepatitis virus infection.

Authors:  Jiehao Zhou; Stephen A Stohlman; Roscoe Atkinson; David R Hinton; Norman W Marten
Journal:  J Virol       Date:  2002-08       Impact factor: 5.103

2.  Analysis of differential immune responses induced by innate and adaptive immunity following transplantation.

Authors:  Hongzhen He; James R Stone; David L Perkins
Journal:  Immunology       Date:  2003-06       Impact factor: 7.397

3.  Analysis of costimulation by 4-1BBL, CD40L, and B7 in graft rejection by gene expression profiles.

Authors:  Rachel DeFina; Kenneth Christopher; Hongzhen He; Didier Mandelbrot; Yongping Gu; Patricia Finn; David L Perkins
Journal:  J Mol Med (Berl)       Date:  2003-08-22       Impact factor: 4.599

4.  Increased expression of MIP-1 alpha and MIP-1 beta mRNAs in the brain correlates spatially and temporally with the spongiform neurodegeneration induced by a murine oncornavirus.

Authors:  S Askovic; C Favara; F J McAtee; J L Portis
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

5.  Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene.

Authors:  K E Peterson; S J Robertson; J L Portis; B Chesebro
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

6.  Chemokine gene expression in astrocytes of Borna disease virus-infected rats and mice in the absence of inflammation.

Authors:  C Sauder; W Hallensleben; A Pagenstecher; S Schneckenburger; L Biro; D Pertlik; J Hausmann; M Suter; P Staeheli
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

7.  Differential chemokine expression following respiratory virus infection reflects Th1- or Th2-biased immunopathology.

Authors:  Fiona J Culley; Alasdair M J Pennycook; John S Tregoning; Tracy Hussell; Peter J M Openshaw
Journal:  J Virol       Date:  2006-05       Impact factor: 5.103

8.  Chemokine gene expression in toll-like receptor-competent and -deficient mice infected with Leishmania major.

Authors:  Simone Antoniazi; Helen P Price; Pascale Kropf; Marina A Freudenberg; Chris Galanos; Deborah F Smith; Ingrid Müller
Journal:  Infect Immun       Date:  2004-09       Impact factor: 3.441
  8 in total

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