Literature DB >> 10669544

New immunopharmacologic approaches to asthma: role of cytokine antagonism.

L J Rosenwasser1.   

Abstract

This article involves an elucidation of the potential inflammatory mechanisms associated with the treatment of allergic disease and asthma, and the possibility of cytokine antagonism as a potential therapeutic mechanism for the treatment of those diseases. There is a review of the role of cytokines in the allergic process and a description of a number of studies done with the capacity of certain cytokine antagonists to develop potential amelioration of immune dysregulation in asthma and atopic states.

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Year:  2000        PMID: 10669544     DOI: 10.1016/s0091-6749(00)90063-0

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  2 in total

1.  Acute 4,4'-Methylene Diphenyl Diisocyanate Exposure-Mediated Downregulation of miR-206-3p and miR-381-3p Activates Inducible Nitric Oxide Synthase Transcription by Targeting Calcineurin/NFAT Signaling in Macrophages.

Authors:  Chen-Chung Lin; Brandon F Law; Justin M Hettick
Journal:  Toxicol Sci       Date:  2020-01-01       Impact factor: 4.849

2.  Interleukin-1beta mediates human airway epithelial cell migration via NF-kappaB.

Authors:  Steven R White; Bernard M Fischer; Bertha A Marroquin; Randi Stern
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2008-10-10       Impact factor: 5.464

  2 in total

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