Literature DB >> 10668869

Internal drainage of giant acute pseudocysts: the role of video-assisted pancreatic necrosectomy.

A Oría1, C Ocampo, H Zandalazini, L Chiappetta, C Morán.   

Abstract

BACKGROUND: Internal drainage of giant pancreatic pseudocysts secondary to acute pancreatitis is frequently complicated with postoperative retroperitoneal infection and hemorrhage. Recent data suggest that the risk factor is unrecognized pancreatic necrosis; presumably, pancreatic necrosis becomes infected with bacteria introduced by the cystoenteric anastomosis. HYPOTHESIS: Video-assisted pancreatic necrosectomy, performed at the time of internal drainage, may prevent postoperative retroperitoneal complications in patients with giant acute pseudocysts.
DESIGN: A consecutive case-series.
SETTING: An urban, university-affiliated, tertiary referral center. PATIENTS: Ten consecutive patients with acute pseudocysts measuring 10 cm or more in major diameter. The mean extent of pancreatic necrosis, as shown by contrast-enhanced computed tomography, was 50%. All patients were operated on electively, at an average time of 7.7 weeks from onset of the attack to surgical treatment. INTERVENTION: Through a midline incision, a 4-cm opening is made at the base of the pseudocyst. Standard laparoscopic instruments are introduced into the pseudocyst and video-assisted pancreatic necrosectomy is performed. The opening is then anastomosed to a Roux-en-Y limb of the jejunum. MAIN OUTCOME MEASURES: Feasibility and safety of video-assisted pancreatic necrosectomy, postoperative morbidity and mortality, hospital stay, and resolution of pseudocysts.
RESULTS: Complete necrosectomy was safely performed throughout. There were neither postoperative retroperitoneal complications nor mortality. Mean hospital stay was 8.2 days and all pseudocysts resolved at a mean follow-up of 6.9 months.
CONCLUSIONS: Video-assisted pancreatic necrosectomy at the time of internal drainage seems to prevent postoperative retroperitoneal complications in patients with giant acute pseudocysts. Depending on appropriate surgical timing, video-assisted necrosectomy is a feasible and safe procedure.

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Year:  2000        PMID: 10668869     DOI: 10.1001/archsurg.135.2.136

Source DB:  PubMed          Journal:  Arch Surg        ISSN: 0004-0010


  8 in total

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6.  A case report of giant pancreatic pseudocyst following acute pancreatitis: experience with endoscopic internal drainage.

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7.  Endoscopic Drainage of Giant Pancreatic Pseudocysts Using Both Lumen-Apposing Metal Stent and Plastic Stent: A Report of Two Cases and Review of the Current Literature.

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8.  Treatment of acute pancreatic pseudocysts after severe acute pancreatitis.

Authors:  Carlos Ocampo; Alejandro Oría; Hugo Zandalazini; Walter Silva; Gustavo Kohan; Luis Chiapetta; Juan Alvarez
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  8 in total

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