Literature DB >> 10668670

Otologic and audiologic evaluation of human immunodeficiency virus-infected patients.

S S Chandrasekhar1, P E Connelly, S S Brahmbhatt, C S Shah, P C Kloser, S Baredes.   

Abstract

PURPOSE: To quantify the incidence of ear disease in patients infected with human immunodeficiency virus (HIV).
MATERIALS AND METHODS: This is a descriptive case series of HIV-positive patients, with data collected using an otologic questionnaire. otologic examination, audiologic evaluation, and chart review. The study was performed at an urban University Hospital's outpatient Infectious Disease and Otolaryngology clinics. A consecutive sample of 50 HIV-infected patients volunteered for this study. Ten subjects refused. Almost all patients received public assistance for medical care. Descriptive results were tabulated. Audiometric data were analyzed for ear, Centers for Disease Control (CDC) group, otologic complaint, and age effects. Data were compared with established norms.
RESULTS: Twenty-three men and 27 women with a mean age of 40 years and mean duration of HIV disease of 3.5 years were studied. Eighteen percent of patients were in category CDC-A, 38% in CDC-B, and 44% in CDC-C. Otologic complaints were more prevalent than expected: 34% of patients reported aural fullness, 32% dizziness, 29% hearing loss, 26% tinnitus, 23% otalgia, and 5% otorrhea. Results of the neuro-otologic examination were abnormal in 33%. Tympanometric examination was abnormal in 21%. A significant degree of high-frequency sensorineural hearing loss was observed. CDC-B and CDC-C patients had worse hearing than CDC-A patients at 3 frequencies. Patients who complained of hearing loss had significantly worse otoacoustic emission results and hearing results than patients who did not, at all frequencies except 1,000 Hz. Patients in their 30s had better hearing in the speech frequencies than did all other patients.
CONCLUSIONS: Ear disease affects up to 33% of HIV-infected patients. Otitis media is a frequent finding. Sensorineural hearing loss is more severe in patients with more severe HIV infection. Patients with ear complaints have demonstrable otopathology. Continuation of this preliminary descriptive work is necessary.

Entities:  

Mesh:

Year:  2000        PMID: 10668670     DOI: 10.1016/s0196-0709(00)80117-9

Source DB:  PubMed          Journal:  Am J Otolaryngol        ISSN: 0196-0709            Impact factor:   1.808


  25 in total

1.  The human immunodeficiency virus reduces network capacity: acoustic noise effect.

Authors:  Dardo Tomasi; Linda Chang; Elisabeth de Castro Caparelli; Frank Telang; Thomas Ernst
Journal:  Ann Neurol       Date:  2006-02       Impact factor: 10.422

2.  Auditory impairments in HIV-infected individuals in Tanzania.

Authors:  Isaac I Maro; Ndeserua Moshi; Odile H Clavier; Todd A MacKenzie; Robert J Kline-Schoder; Jed C Wilbur; Robert D Chambers; Abigail M Fellows; Benjamin G Jastrzembski; John E Mascari; Muhammad Bakari; Mecky Matee; Frank E Musiek; Richard D Waddell; C Fordham von Reyn; Jay C Buckey
Journal:  Ear Hear       Date:  2014 May-Jun       Impact factor: 3.570

3.  Hearing loss among HIV-seropositive and HIV-seronegative men and women.

Authors:  Peter Torre; Howard J Hoffman; Gayle Springer; Christopher Cox; Mary A Young; Joseph B Margolick; Michael Plankey
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2015-03       Impact factor: 6.223

4.  Squamous cell carcinoma of the larynx in HIV-positive patients: difficulties in diagnosis and management.

Authors:  E J S M Blenke; W A Clement; J M Andrews; E Scanlon; G A Vernham
Journal:  Dysphagia       Date:  2006-11-01       Impact factor: 3.438

5.  Noise-induced hearing loss in mice treated with antiretroviral drugs.

Authors:  Devrim Bektas; Glen K Martin; Barden B Stagner; Brenda L Lonsbury-Martin
Journal:  Hear Res       Date:  2008-02-08       Impact factor: 3.208

6.  Auditory Impairments in HIV-Infected Children.

Authors:  Isaac I Maro; Abigail M Fellows; Odile H Clavier; Jiang Gui; Catherine C Rieke; Jed C Wilbur; Robert D Chambers; Benjamin G Jastrzembski; John E Mascari; Muhammad Bakari; Mecky Matee; Frank E Musiek; Richard D Waddell; C Fordham von Reyn; Paul E Palumbo; Ndeserua Moshi; Jay C Buckey
Journal:  Ear Hear       Date:  2016 Jul-Aug       Impact factor: 3.570

7.  Audiological manifestations in HIV-positive adults.

Authors:  Carla Gentile Matas; Rosanna Giaffredo Angrisani; Fernanda Cristina Leite Magliaro; Aluisio Augusto Cotrim Segurado
Journal:  Clinics (Sao Paulo)       Date:  2014-07       Impact factor: 2.365

8.  An analysis of auditory manifestations in a group of adults with AIDS prior to antiretroviral therapy.

Authors:  Katijah Khoza-Shangase
Journal:  Afr J Infect Dis       Date:  2011

9.  Audio-vestibular function in human immunodeficiency virus infected patients in India.

Authors:  Suma Susan Mathews; Rita Ruby Albert; Anand Job
Journal:  Indian J Sex Transm Dis AIDS       Date:  2012-07

10.  HIV: An Epidemiologic study on Head and Neck Involvement in 50 Patients.

Authors:  Mehdi Bakhshaee; Mohammad Reza Sarvghad; Kamran Khazaeni; Rahman Movahed; Ali Mohammad Hoseinpour
Journal:  Iran J Otorhinolaryngol       Date:  2014-04
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.