Literature DB >> 10668186

Anticonvulsant activity of analogues of acetazolamide.

E E Chufán1, J C Pedregosa, O N Baldini, L Bruno-Blanch.   

Abstract

The anticonvulsant activity of 5-tertbutyloxycarbonylamido-1,3,4-thiadiazole-2-sulfonamide (B-H2ats) and 5-amino-1,3,4-thiadiazole-2-sulfonamide (Hats) was compared in mice, to that of acetazolamide (H2acm). These compounds exhibit potent anticonvulsant activity and low minimal motor impairment.

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Year:  1999        PMID: 10668186     DOI: 10.1016/s0014-827x(99)00096-8

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  1 in total

1.  Synthesis of new 1,3,4-thiadiazole and 1,2,3,4-oxathiadiazole derivatives from carbohydrate precursors and study of their effect on tyrosinase enzyme.

Authors:  Mohamed M El-Sadek; Seham Y Hassan; Huda E Abdelwahab; Galila A Yacout
Journal:  Molecules       Date:  2012-07-11       Impact factor: 4.411

  1 in total

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