Literature DB >> 10667911

The role of NAC in amyloidogenesis in Alzheimer's disease.

M Hashimoto, T Takenouchi, M Mallory, E Masliah, A Takeda.   

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Year:  2000        PMID： 10667911      PMCID： PMC1850022          DOI： 10.1016/s0002-9440(10)64777-3

Source DB:  PubMed          Journal:  Am J Pathol        ISSN： 0002-9440            Impact factor:   4.307


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  10 in total

1.  The N-terminal region of non-A beta component of Alzheimer's disease amyloid is responsible for its tendency to assume beta-sheet and aggregate to form fibrils.

Authors:  O M El-Agnaf; A M Bodles; D J Guthrie; P Harriott; G B Irvine
Journal:  Eur J Biochem       Date:  1998-11-15

2.  C-terminal alpha-synuclein immunoreactivity in structures other than Lewy bodies in neurodegenerative disorders.

Authors:  A Takeda; M Hashimoto; M Mallory; M Sundsumo; L Hansen; E Masliah
Journal:  Acta Neuropathol       Date:  2000-03       Impact factor: 17.088

3.  The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?

Authors:  H Han; P H Weinreb; P T Lansbury
Journal:  Chem Biol       Date:  1995-03

4.  Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.

Authors:  T A Bayer; P Jäkälä; T Hartmann; L Havas; C McLean; J G Culvenor; Q X Li; C L Masters; P Falkai; K Beyreuther
Journal:  Neurosci Lett       Date:  1999-05-14       Impact factor: 3.046

5.  Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

Authors:  J G Culvenor; C A McLean; S Cutt; B C Campbell; F Maher; P Jäkälä; T Hartmann; K Beyreuther; C L Masters; Q X Li
Journal:  Am J Pathol       Date:  1999-10       Impact factor: 4.307

Review 6.  Alpha-synuclein in Lewy body disease and Alzheimer's disease.

Authors:  M Hashimoto; E Masliah
Journal:  Brain Pathol       Date:  1999-10       Impact factor: 6.508

7.  Non-A beta component of Alzheimer's disease amyloid (NAC) is amyloidogenic.

Authors:  A Iwai; M Yoshimoto; E Masliah; T Saitoh
Journal:  Biochemistry       Date:  1995-08-15       Impact factor: 3.162

8.  Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease.

Authors:  E Masliah; A Iwai; M Mallory; K Uéda; T Saitoh
Journal:  Am J Pathol       Date:  1996-01       Impact factor: 4.307

9.  Abnormal distribution of the non-Abeta component of Alzheimer's disease amyloid precursor/alpha-synuclein in Lewy body disease as revealed by proteinase K and formic acid pretreatment.

Authors:  A Takeda; M Hashimoto; M Mallory; M Sundsumo; L Hansen; A Sisk; E Masliah
Journal:  Lab Invest       Date:  1998-09       Impact factor: 5.662

10.  Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease.

Authors:  K Uéda; H Fukushima; E Masliah; Y Xia; A Iwai; M Yoshimoto; D A Otero; J Kondo; Y Ihara; T Saitoh
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-01       Impact factor: 11.205
  10 in total
  11 in total

1.  Coupling of the non-amyloid-component (NAC) domain and the KTK(E/Q)GV repeats stabilize the α-synuclein fibrils.

Authors:  Liang Xu; Ruth Nussinov; Buyong Ma
Journal:  Eur J Med Chem       Date:  2016-01-25       Impact factor: 6.514

2.  Deciphering the Biochemical Pathway and Pharmacokinetic Study of Amyloid βeta-42 with Superparamagnetic Iron Oxide Nanoparticles (SPIONs) Using Systems Biology Approach.

Authors:  Aman Chandra Kaushik; Ajay Kumar; Vivek Dhar Dwivedi; Shiv Bharadwaj; Sanjay Kumar; Kritika Bharti; Pavan Kumar; Ravi Kumar Chaudhary; Sarad Kumar Mishra
Journal:  Mol Neurobiol       Date:  2017-05-06       Impact factor: 5.590

3.  Familial Mutations May Switch Conformational Preferences in α-Synuclein Fibrils.

Authors:  Liang Xu; Buyong Ma; Ruth Nussinov; Damien Thompson
Journal:  ACS Chem Neurosci       Date:  2017-01-27       Impact factor: 4.418

Review 4.  Neuropathological alterations in Alzheimer disease.

Authors:  Alberto Serrano-Pozo; Matthew P Frosch; Eliezer Masliah; Bradley T Hyman
Journal:  Cold Spring Harb Perspect Med       Date:  2011-09       Impact factor: 6.915

5.  Predictive Modeling of Neurotoxic α-Synuclein Polymorphs.

Authors:  Liang Xu; Shayon Bhattacharya; Damien Thompson
Journal:  Methods Mol Biol       Date:  2022

6.  Characterization of Amyloidogenic Peptide Aggregability in Helical Subspace.

Authors:  Shayon Bhattacharya; Liang Xu; Damien Thompson
Journal:  Methods Mol Biol       Date:  2022

Review 7.  The many faces of α-synuclein: from structure and toxicity to therapeutic target.

Authors:  Hilal A Lashuel; Cassia R Overk; Abid Oueslati; Eliezer Masliah
Journal:  Nat Rev Neurosci       Date:  2013-01       Impact factor: 34.870

8.  Role of synucleins in Alzheimer's disease.

Authors:  Leslie Crews; Igor Tsigelny; Makoto Hashimoto; Eliezer Masliah
Journal:  Neurotox Res       Date:  2009-06-24       Impact factor: 3.911

9.  Lack of alpha-synuclein increases amyloid plaque accumulation in a transgenic mouse model of Alzheimer's disease.

Authors:  Verena Kallhoff; Erica Peethumnongsin; Hui Zheng
Journal:  Mol Neurodegener       Date:  2007-03-16       Impact factor: 14.195

10.  Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner.

Authors:  Sandeep K Sharma; Erik Chorell; Pär Steneberg; Emma Vernersson-Lindahl; Helena Edlund; Pernilla Wittung-Stafshede
Journal:  Sci Rep       Date:  2015-07-31       Impact factor: 4.379
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