Literature DB >> 10667385

Central role of arachidonate 5-lipoxygenase in the regulation of cell growth and apoptosis in human prostate cancer cells.

J Ghosh1, C E Myers.   

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Year:  1999        PMID: 10667385     DOI: 10.1007/978-1-4615-4793-8_84

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


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  11 in total

1.  Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon.

Authors:  Sivalokanathan Sarveswaran; Vijayalakshmi Thamilselvan; Chaya Brodie; Jagadananda Ghosh
Journal:  Biochim Biophys Acta       Date:  2011-07-30

2.  Membrane fluidity is a key modulator of membrane binding, insertion, and activity of 5-lipoxygenase.

Authors:  Abhay H Pande; Shan Qin; Suren A Tatulian
Journal:  Biophys J       Date:  2005-03-18       Impact factor: 4.033

3.  Inhibition of 5-lipoxygenase selectively triggers disruption of c-Myc signaling in prostate cancer cells.

Authors:  Sivalokanathan Sarveswaran; Debrup Chakraborty; Dhananjay Chitale; Rosalie Sears; Jagadananda Ghosh
Journal:  J Biol Chem       Date:  2014-12-24       Impact factor: 5.157

4.  5-Lipoxygenase and leukotriene B(4) receptor are expressed in human pancreatic cancers but not in pancreatic ducts in normal tissue.

Authors:  René Hennig; Xian-Zhong Ding; Wei-Gang Tong; Matthias B Schneider; Jens Standop; Helmut Friess; Markus W Büchler; Parviz M Pour; Thomas E Adrian
Journal:  Am J Pathol       Date:  2002-08       Impact factor: 4.307

5.  Down-regulation of vinculin upon MK886-induced apoptosis in LN18 glioblastoma cells.

Authors:  A M Magro; A D Magro; C Cunningham; M R Miller
Journal:  Neoplasma       Date:  2007       Impact factor: 2.575

6.  OXER1, a G protein-coupled oxoeicosatetraenoid receptor, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells.

Authors:  Sivalokanathan Sarveswaran; Jagadananda Ghosh
Journal:  Cancer Lett       Date:  2013-05-02       Impact factor: 8.679

7.  MK591, a second generation leukotriene biosynthesis inhibitor, prevents invasion and induces apoptosis in the bone-invading C4-2B human prostate cancer cells: implications for the treatment of castration-resistant, bone-metastatic prostate cancer.

Authors:  Sivalokanathan Sarveswaran; Ritisha Ghosh; Shravan Morisetty; Jagadananda Ghosh
Journal:  PLoS One       Date:  2015-04-15       Impact factor: 3.240

8.  The Role of PPARgamma Receptors and Leukotriene B(4) Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer.

Authors:  Thomas E Adrian; Rene Hennig; Helmut Friess; Xianzhong Ding
Journal:  PPAR Res       Date:  2009-01-27       Impact factor: 4.964

9.  Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt.

Authors:  Sivalokanathan Sarveswaran; Subhash C Gautam; Jagadananda Ghosh
Journal:  Int J Oncol       Date:  2012-10-16       Impact factor: 5.650

Review 10.  Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer.

Authors:  Xian-Zhong Ding; Rene Hennig; Thomas E Adrian
Journal:  Mol Cancer       Date:  2003-01-07       Impact factor: 27.401

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