| Literature DB >> 10666278 |
B Parra1, M T Lin, S A Stohlman, C C Bergmann, R Atkinson, D R Hinton.
Abstract
The pathogenesis of the neurotropic strain of mouse hepatitis virus in Fas-deficient mice suggested that Fas-mediated cytotoxicity may be required during viral clearance after the loss of perforin-mediated cytotoxicity. The absence of both Fas- and perforin-mediated cytolysis resulted in an uncontrolled infection, suggesting a redundancy of cytolytic pathways to control virus replication.Entities:
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Year: 2000 PMID: 10666278 PMCID: PMC111729 DOI: 10.1128/jvi.74.5.2447-2450.2000
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103