| Literature DB >> 10666277 |
J Xu1, A Ahmad, J F Jones, R Dolcetti, E Vaccher, U Prasad, J Menezes.
Abstract
Transforming growth factor beta (TGF-beta) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-beta in various EBV-associated diseases correlating positively with EBV-specific IgA titers and negatively with IgM titers, suggesting a role for this cytokine in the pathogenesis of these diseases.Entities:
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Year: 2000 PMID: 10666277 PMCID: PMC111728 DOI: 10.1128/jvi.74.5.2443-2446.2000
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103