Literature DB >> 10666277

Elevated serum transforming growth factor beta1 levels in Epstein-Barr virus-associated diseases and their correlation with virus-specific immunoglobulin A (IgA) and IgM.

J Xu1, A Ahmad, J F Jones, R Dolcetti, E Vaccher, U Prasad, J Menezes.   

Abstract

Transforming growth factor beta (TGF-beta) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-beta in various EBV-associated diseases correlating positively with EBV-specific IgA titers and negatively with IgM titers, suggesting a role for this cytokine in the pathogenesis of these diseases.

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Year:  2000        PMID: 10666277      PMCID: PMC111728          DOI: 10.1128/jvi.74.5.2443-2446.2000

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  26 in total

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7.  Elevated serum levels of transforming growth factor beta1 in Epstein-Barr virus-associated nasopharyngeal carcinoma patients.

Authors:  J Xu; J Menezes; U Prasad; A Ahmad
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Review 10.  Interleukin-10.

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7.  High FMNL3 expression promotes nasopharyngeal carcinoma cell metastasis: role in TGF-β1-induced epithelia-to-mesenchymal transition.

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