Literature DB >> 10664857

Nucleotide sequence of cDNA coding the mitochondrial precursor protein of the ATPase inhibitor from humans.

N Ichikawa1, S Ushida, M Kawabata, Y Masazumi.   

Abstract

Mitochondrial ATP synthase (F1Fo-ATPase) is regulated by an intrinsic ATPase inhibitor protein. In the present study, cDNA coding the human homolog of the inhibitor protein was isolated and sequenced. The deduced protein sequence shows that the protein was composed of 106 amino acids and had a molecular weight of 12248. The structural features of the protein show that the cDNA isolated in this study codes the human ATPase inhibitor.

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Year:  1999        PMID： 10664857     DOI： 10.1271/bbb.63.2225

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  11 in total

1.  Assessing actual contribution of IF1, inhibitor of mitochondrial FoF1, to ATP homeostasis, cell growth, mitochondrial morphology, and cell viability.

Authors:  Makoto Fujikawa; Hiromi Imamura; Junji Nakamura; Masasuke Yoshida
Journal:  J Biol Chem       Date:  2012-04-09       Impact factor: 5.157

2.  The inhibitor protein (IF1) of the F1F0-ATPase modulates human osteosarcoma cell bioenergetics.

Authors:  Simona Barbato; Gianluca Sgarbi; Giulia Gorini; Alessandra Baracca; Giancarlo Solaini
Journal:  J Biol Chem       Date:  2015-01-20       Impact factor: 5.157

3.  Caenorhabditis elegans MAI-1 protein, which is similar to mitochondrial ATPase inhibitor (IF1), can inhibit yeast F0F1-ATPase but cannot be transported to yeast mitochondria.

Authors:  Naoki Ichikawa; Chiyoko Ando; Mina Fumino
Journal:  J Bioenerg Biomembr       Date:  2006-08-02       Impact factor: 2.945

4.  The region from phenylalanine-28 to lysine-50 of a yeast mitochondrial ATPase inhibitor (IF1) forms an α-helix in solution.

Authors:  Li Sun; Naomi Nakamae; Naoki Ichikawa
Journal:  J Bioenerg Biomembr       Date:  2015-09-29       Impact factor: 2.945

5.  Overexpression, purification, and characterization of human and bovine mitochondrial ATPase inhibitors: comparison of the properties of mammalian and yeast ATPase inhibitors.

Authors:  Naoki Ichikawa; Chikae Ogura
Journal:  J Bioenerg Biomembr       Date:  2003-10       Impact factor: 2.945

6.  IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice.

Authors:  Junji Nakamura; Makoto Fujikawa; Masasuke Yoshida
Journal:  Biosci Rep       Date:  2013-09-17       Impact factor: 3.840

7.  Trypanosoma brucei TbIF1 inhibits the essential F1-ATPase in the infectious form of the parasite.

Authors:  Brian Panicucci; Ondřej Gahura; Alena Zíková
Journal:  PLoS Negl Trop Dis       Date:  2017-04-17

8.  Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells.

Authors:  Anežka Kahancová; Filip Sklenář; Petr Ježek; Andrea Dlasková
Journal:  Sci Rep       Date:  2020-01-31       Impact factor: 4.379

9.  Molecular Regulation of the Mitochondrial F(1)F(o)-ATPsynthase: Physiological and Pathological Significance of the Inhibitory Factor 1 (IF(1)).

Authors:  Danilo Faccenda; Michelangelo Campanella
Journal:  Int J Cell Biol       Date:  2012-08-26

10.  F1F0-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation.

Authors:  Helen Tanton; Svetlana Voronina; Anthony Evans; Jane Armstrong; Robert Sutton; David N Criddle; Lee Haynes; Michael C Schmid; Fiona Campbell; Eithne Costello; Alexei V Tepikin
Journal:  Front Physiol       Date:  2018-07-11       Impact factor: 4.566
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