Literature DB >> 10664847

Improvement of the physical properties of pepsin-solubilized elastin-collagen film by crosslinking.

K Takahashi1, Y Nakata, K Someya, M Hattori.   

Abstract

Pepsin-solubilized elastin (PSE)-conjugated collagen film was prepared from a collagen matrix with PSE by drying it and crosslinking the constituents with water-soluble carbodiimide or microbial transglutaminase to improve the physical properties of the collagen film. The crosslinking reduced the solubility and improved the thermal stability, the thermal transition properties, and the elasticity of the control film in water. In particular, water-soluble carbodiimide strongly influenced these properties. The PSE-conjugated collagen film showed good permeation by water-soluble tasting substances such as oligosaccharides and amino acids, but poor permeation by polysaccharide, protein, and hydrophobic substances such as retinol and cholesterol.

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Year:  1999        PMID： 10664847     DOI： 10.1271/bbb.63.2144

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  6 in total

1.  Characterization of esterified hyaluronan-gelatin polymer composites suitable for chondrogenic differentiation of mesenchymal stem cells.

Authors:  Peter Angele; Rainer Müller; Detlef Schumann; Carsten Englert; Johannes Zellner; Brian Johnstone; Jung Yoo; Joachim Hammer; Johann Fierlbeck; Martin K Angele; Michael Nerlich; Richard Kujat
Journal:  J Biomed Mater Res A       Date:  2009-11       Impact factor: 4.396

2.  The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen.

Authors:  Jean-Daniel Malcor; Daniel Bax; Samir W Hamaia; Natalia Davidenko; Serena M Best; Ruth E Cameron; Richard W Farndale; Dominique Bihan
Journal:  Biomaterials       Date:  2016-01-23       Impact factor: 12.479

3.  Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF.

Authors:  Jean-Daniel Malcor; Victoria Juskaite; Despoina Gavriilidou; Emma J Hunter; Natalia Davidenko; Samir Hamaia; Sanjay Sinha; Ruth E Cameron; Serena M Best; Birgit Leitinger; Richard W Farndale
Journal:  Biomaterials       Date:  2018-07-31       Impact factor: 12.479

4.  Crosslinking and composition influence the surface properties, mechanical stiffness and cell reactivity of collagen-based films.

Authors:  Chloe N Grover; Jessica H Gwynne; Nicholas Pugh; Samir Hamaia; Richard W Farndale; Serena M Best; Ruth E Cameron
Journal:  Acta Biomater       Date:  2012-05-12       Impact factor: 8.947

5.  Collagen scaffolds functionalized with triple-helical peptides support 3D HUVEC culture.

Authors:  Jean-Daniel Malcor; Emma J Hunter; Natalia Davidenko; Daniel V Bax; Ruth Cameron; Serena Best; Sanjay Sinha; Richard W Farndale
Journal:  Regen Biomater       Date:  2020-08-18

6.  Modulating hESC-derived cardiomyocyte and endothelial cell function with triple-helical peptides for heart tissue engineering.

Authors:  Maria Colzani; Jean-Daniel Malcor; Emma J Hunter; Semih Bayraktar; Murray Polkinghorne; Thomas Krieg; Ruth Cameron; Serena Best; Richard W Farndale; Sanjay Sinha
Journal:  Biomaterials       Date:  2020-12-16       Impact factor: 12.479
  6 in total

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