Literature DB >> 10664606

FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation.

V Brinkmann1, D Pinschewer, K Chiba, L Feng.   

Abstract

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Year:  2000        PMID： 10664606     DOI： 10.1016/s0165-6147(99)01419-4

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


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  32 in total

Review 1.  Role of chemokines in inflammation and immunoregulation.

Authors:  L Feng
Journal:  Immunol Res       Date:  2000       Impact factor: 2.829

Review 2.  A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya).

Authors:  Jerold Chun; Volker Brinkmann
Journal:  Discov Med       Date:  2011-09       Impact factor: 2.970

Review 3.  Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

Authors:  Volker Brinkmann; Andreas Billich; Thomas Baumruker; Peter Heining; Robert Schmouder; Gordon Francis; Shreeram Aradhye; Pascale Burtin
Journal:  Nat Rev Drug Discov       Date:  2010-10-29       Impact factor: 84.694

4.  Activation of sphingosine-1-phosphate 1 receptor in the proximal tubule protects against ischemia-reperfusion injury.

Authors:  Amandeep Bajwa; Sang-Kyung Jo; Hong Ye; Liping Huang; Krishna R Dondeti; Diane L Rosin; Volker H Haase; Timothy L Macdonald; Kevin R Lynch; Mark D Okusa
Journal:  J Am Soc Nephrol       Date:  2010-03-25       Impact factor: 10.121

5.  The effect of a novel immunosuppressant, FTY720, in mice without secondary lymphoid organs.

Authors:  Kiminobu Sugito; Tsugumichi Koshinaga; Mikiya Inoue; Taro Ikeda; Noritsugu Hagiwara; Masahiro Fukuzawa
Journal:  Surg Today       Date:  2005       Impact factor: 2.549

6.  An investigation of the impact of the location and timing of antigen-specific T cell division on airways inflammation.

Authors:  S Hutchison; B S W Choo-Kang; V B Gibson; R V Bundick; A J Leishman; J M Brewer; I B McInnes; P Garside
Journal:  Clin Exp Immunol       Date:  2009-01       Impact factor: 4.330

Review 7.  The influence of sphingosine-1-phosphate receptor signaling on lymphocyte trafficking: how a bioactive lipid mediator grew up from an "immature" vascular maturation factor to a "mature" mediator of lymphocyte behavior and function.

Authors:  Michael D Davis; John H Kehrl
Journal:  Immunol Res       Date:  2009       Impact factor: 2.829

8.  The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells.

Authors:  Cuiyan Xin; Shuyu Ren; Wolfgang Eberhardt; Josef Pfeilschifter; Andrea Huwiler
Journal:  Br J Pharmacol       Date:  2006-01       Impact factor: 8.739

9.  1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization.

Authors:  Inna V Grishkan; Amanda N Fairchild; Peter A Calabresi; Anne R Gocke
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-09       Impact factor: 11.205

Review 10.  Infection risk in patients on multiple sclerosis therapeutics.

Authors:  Eric M Williamson; Joseph R Berger
Journal:  CNS Drugs       Date:  2015-03       Impact factor: 5.749
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