Literature DB >> 10664453

Cross-talk between posttranscriptionally silenced neomycin phosphotransferase II transgenes.

H Van Houdt1, A Kovarík, M Van Montagu, A Depicker.   

Abstract

Tobacco plants containing a transgene locus with two chimeric neomycin phosphotransferase II (nptII) genes in tail-to-tail orientation (locus 1) show posttranscriptional gene silencing. The silenced nptII transgenes of locus 1 can downregulate the expression of homologous nptII transgenes in hybrid plants. The 3' region of the silenced nptII genes located in the center of the inverted repeat locus 1 is extensively methylated. Moreover, 3' segments of in trans-inactivated transgenes also become methylated, suggesting cross-talk between homologous posttranscriptionally silenced genes. Our results are in accordance with the hypothesis that this cross-talk can be mediated by specially featured RNAs.

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Year:  2000        PMID： 10664453     DOI： 10.1016/s0014-5793(00)01076-0

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  10 in total

1.  Transgene silencing of invertedly repeated transgenes is released upon deletion of one of the transgenes involved.

Authors:  S De Buck; M Van Montagu; A Depicker
Journal:  Plant Mol Biol       Date:  2001-07       Impact factor: 4.076

2.  Coincident sequence-specific RNA degradation of linked transgenes in the plant genome.

Authors:  Megumi Kasai; Maiko Koseki; Kazunori Goto; Chikara Masuta; Shiho Ishii; Roger P Hellens; Akito Taneda; Akira Kanazawa
Journal:  Plant Mol Biol       Date:  2011-12-07       Impact factor: 4.076

3.  RNA target sequences promote spreading of RNA silencing.

Authors:  Helena Van Houdt; Annick Bleys; Anna Depicker
Journal:  Plant Physiol       Date:  2003-01       Impact factor: 8.340

4.  Dedifferentiation of tobacco cells is associated with ribosomal RNA gene hypomethylation, increased transcription, and chromatin alterations.

Authors:  Blazena Koukalova; Miloslava Fojtova; Kar Yoong Lim; Jaroslav Fulnecek; Andrew Rowland Leitch; Ales Kovarik
Journal:  Plant Physiol       Date:  2005-08-19       Impact factor: 8.340

5.  Evaluation of CRE-mediated excision approaches in Arabidopsis thaliana.

Authors:  Gordana Marjanac; Annelies De Paepe; Ingrid Peck; Anni Jacobs; Sylvie De Buck; Anna Depicker
Journal:  Transgenic Res       Date:  2007-05-31       Impact factor: 2.788

6.  Epigenetic switch from posttranscriptional to transcriptional silencing is correlated with promoter hypermethylation.

Authors:  Miloslava Fojtova; Helena Van Houdt; Anna Depicker; Ales Kovarik
Journal:  Plant Physiol       Date:  2003-10-09       Impact factor: 8.340

7.  Epigenetic switches of tobacco transgenes associate with transient redistribution of histone marks in callus culture.

Authors:  Kateřina Křížová; Ann Depicker; Aleš Kovařík
Journal:  Epigenetics       Date:  2013-04-26       Impact factor: 4.528

8.  Cell culture-induced gradual and frequent epigenetic reprogramming of invertedly repeated tobacco transgene epialleles.

Authors:  Katerina Krizova; Miloslava Fojtova; Ann Depicker; Ales Kovarik
Journal:  Plant Physiol       Date:  2009-01-07       Impact factor: 8.340

9.  Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing.

Authors:  Lucie Crhák Khaitová; Miloslava Fojtová; Kateřina Křížová; Jana Lunerová; Jaroslav Fulneček; Anna Depicker; Aleš Kovařík
Journal:  Epigenetics       Date:  2011-05-01       Impact factor: 4.528

10.  The trans-silencing capacity of invertedly repeated transgenes depends on their epigenetic state in tobacco.

Authors:  Miloslava Fojtová; Annick Bleys; Jana Bedrichová; Helena Van Houdt; Katerina Krízová; Anna Depicker; Ales Kovarík
Journal:  Nucleic Acids Res       Date:  2006-05-02       Impact factor: 16.971
  10 in total

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