Ruptured exomphalos and gastroschisis: a retrospective analysis of morbidity and mortality in Nigerian children.

The survival of infants with major abdominal-wall defects (AWD) has improved over the years in developed countries. In Zaria, northern Nigeria, survival from intact exomphalos (EX), has improved with the adoption of non-operative management. Ruptured EX (REX) and gastroschisis (GS), however, remain problematic. This is a report of the mortality in REX and GS in a retrospective review of 16 infants with REX and 14 with GS managed over 10 years at the Ahmadu Bello University Teaching Hospital, Zaria. The median age at presentation was 3 days and 24 h for REX and GS, respectively; 29 of the 30 patients were delivered at home. Two patients with REX and 4 with GS had associated anomalies involving mostly the gastrointestinal tract. Bowel or omental strangulation occurred in 13 patients, resulting in gangrene in 8. Fascial closure was achieved in 20 patients, skin closure only in 4, and in 4 improvised silo coverage was used, the latter associated with high infection rate. Neonatal intensive care units (NICU) and total parenteral nutrition (TPN) were not available. The overall mortality was 18.6% (gastroschisis 10, ruptured exomphalos 8, 11 from sepsis and 7 due to respiratory embarrassment). The management of these AWDs thus continues to be problematic in our environment, and mortality remains high. Provision of more modern supportive facilities (NICU and TPN) may improve the survival in our and similar environments.